为大模型多智能体系统设计了新型强化微调方法，提升协作与推理能力。

Large Language Model (LLM)-based Multi-Agent Systems (LaMAS) have demonstrated strong capabilities on complex agentic tasks requiring multifaceted reasoning and collaboration, from high-quality presentation generation to scientific research. Meanwhile, Reinforcement Learning (RL) is widely recognized for enhancing agent intelligence, but limited work has studied fine-tuning LaMAS with foundational RL techniques. Directly applying conventional Multi-Agent Reinforcement Learning (MARL) to LaMAS also introduces major challenges due to the unique mechanisms of LaMAS. To address these challenges, this article presents a comprehensive study of LLM-based MARL and proposes Multi-Agent Reinforcement Fine-Tuning (MARFT). We introduce Flex-MG, a new Markov Game formulation aligned with real-world LaMAS optimization, together with a universal algorithmic framework tailored to LaMAS. We review the evolution from traditional RL to Reinforcement Fine-Tuning (RFT), then analyze the multi-agent counterpart. For LaMAS, we identify key differences between classical MARL and MARFT, including asynchronous agent interactions, profile-aware agent design, and heterogeneous architectures. These differences motivate a LaMAS-oriented formulation of RFT. We present a robust and scalable MARFT framework, detail its modular algorithm, and provide an open-source implementation to support adoption and further research. The paper further discusses application perspectives and open challenges, including dynamic environment modeling, sample inefficiency, and the lack of cohesive frameworks. By connecting theoretical foundations with practical methodology, this work aims to serve as a roadmap for advancing MARFT toward resilient, adaptive, and human-aligned agentic systems. Implementation: https://github.com/jwliao-ai/MARFT.