arXiv:2504.18631cs.AIcs.LG2025-04被引 15

用时序数据融合与群体策略优化,生成更精准的个性化医疗方案

Research on Personalized Medical Intervention Strategy Generation System based on Group Relative Policy Optimization and Time-Series Data Fusion

  • 基于群体相对策略优化,动态平衡个体与群体治疗收益
  • 多模态时序数据通过自注意力与可微门控网络实现高效融合
  • 结合遗传算法与蒙特卡洛树搜索,全局优化干预策略

针对高维异构时序医疗数据下个性化干预方案的及时生成这一关键挑战,本文提出一种基于群组相对策略优化(GRPO)与时序数据融合的个性化医疗干预策略生成系统。首先,在策略梯度更新中引入组间相对策略约束,自适应平衡个体与群体收益;为提升决策鲁棒性与可解释性,采用多层神经网络对患者特征进行分组编码。其次,针对多源异构时序数据的快速多模态融合,设计结合多通道神经网络与自注意力机制的动态特征提取框架,并通过可微门控网络实现关键特征筛选与聚合。最后,提出融合遗传算法与蒙特卡洛树搜索的协同搜索机制,实现干预策略的全局优化。实验表明,该系统在准确率、覆盖率及决策效益方面均显著优于现有方法。

原文摘要 · Abstract (English)

With the timely formation of personalized intervention plans based on high-dimensional heterogeneous time series information becoming an important challenge in the medical field today, electronic medical records, wearables, and other multi-source medical data are increasingly generated and diversified. In this work, we develop a system to generate personalized medical intervention strategies based on Group Relative Policy Optimization (GRPO) and Time-Series Data Fusion. First, by incorporating relative policy constraints among the groups during policy gradient updates, we adaptively balance individual and group gains. To improve the robustness and interpretability of decision-making, a multi-layer neural network structure is employed to group-code patient characteristics. Second, for the rapid multi-modal fusion of multi-source heterogeneous time series, a multi-channel neural network combined with a self-attention mechanism is used for dynamic feature extraction. Key feature screening and aggregation are achieved through a differentiable gating network. Finally, a collaborative search process combining a genetic algorithm and Monte Carlo tree search is proposed to find the ideal intervention strategy, achieving global optimization. Experimental results show significant improvements in accuracy, coverage, and decision-making benefits compared with existing methods.

个性化医疗时序融合策略优化智能决策

Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。