模仿原生动物行为的新优化算法，解决工程难题效果出色。

This study proposes a novel artificial protozoa optimizer (APO) that is inspired by protozoa in nature. The APO mimics the survival mechanisms of protozoa by simulating their foraging, dormancy, and reproductive behaviors. The APO was mathematically modeled and implemented to perform the optimization processes of metaheuristic algorithms. The performance of the APO was verified via experimental simulations and compared with 32 state-of-the-art algorithms. Wilcoxon signed-rank test was performed for pairwise comparisons of the proposed APO with the state-of-the-art algorithms, and Friedman test was used for multiple comparisons. First, the APO was tested using 12 functions of the 2022 IEEE Congress on Evolutionary Computation benchmark. Considering practicality, the proposed APO was used to solve five popular engineering design problems in a continuous space with constraints. Moreover, the APO was applied to solve a multilevel image segmentation task in a discrete space with constraints. The experiments confirmed that the APO could provide highly competitive results for optimization problems. The source codes of Artificial Protozoa Optimizer are publicly available at https://seyedalimirjalili.com/projects and https://ww2.mathworks.cn/matlabcentral/fileexchange/162656-artificial-protozoa-optimizer.