首个面向真实场景的反编译器评估基准，验证LLM在可读性上的优势。

Decompilers are fundamental tools for critical security tasks, from vulnerability discovery to malware analysis, yet their evaluation remains fragmented. Existing approaches primarily focus on syntactic correctness through synthetic micro-benchmarks or subjective human ratings, failing to address real-world requirements for semantic fidelity and analyst usability. We present DecompileBench, the first comprehensive framework that enables effective evaluation of decompilers in reverse engineering workflows through three key components: \textit{real-world function extraction} (comprising 23,400 functions from 130 real-world programs), \textit{runtime-aware validation}, and \textit{automated human-centric assessment} using LLM-as-Judge to quantify the effectiveness of decompilers in reverse engineering workflows. Through a systematic comparison between six industrial-strength decompilers and six recent LLM-powered approaches, we demonstrate that LLM-based methods surpass commercial tools in code understandability despite 52.2% lower functionality correctness. These findings highlight the potential of LLM-based approaches to transform human-centric reverse engineering. We open source \href{https://github.com/Jennieett/DecompileBench}{DecompileBench} to provide a framework to advance research on decompilers and assist security experts in making informed tool selections based on their specific requirements.