arXiv:2505.13875eess.IVcs.CV2025-05被引 2

用AI自动评估宫颈涂片质量,比人工更准更快。

Automated Quality Evaluation of Cervical Cytopathology Whole Slide Images Based on Content Analysis

  • 基于TBS标准,融合检测、分类与分割模型分析涂片上下文。
  • 100张切片测试中,评估速度与一致性显著优于人工。
  • 适合病理医生辅助筛查,提升宫颈癌早诊效率。

液基细胞学检查(TCT)是宫颈癌筛查最常用方法,样本质量直接影响诊断准确性。传统人工评估依赖病理医生显微镜观察,存在主观性强、成本高、耗时长、可靠性低等问题。随着计算机辅助诊断(CAD)的发展,亟需一种能达到专业病理医生水平的自动化质量评估系统。为此,本文提出一种基于《巴氏系统》(TBS)标准、人工智能算法及临床数据特征的宫颈细胞病理全切片图像(WSI)全自动质量评估方法。该方法通过多模型(目标检测、分类、分割)分析WSI上下文,量化TBS关注的质量指标,如染色质量、细胞数量和细胞占比。随后,利用XGBoost模型挖掘病理医生对不同质量指标的关注度,构建综合样本评分模型。在100张WSI上的实验表明,该方法在速度与一致性方面具有显著优势。

原文摘要 · Abstract (English)

The ThinPrep Cytologic Test (TCT) is the most widely used method for cervical cancer screening, and the sample quality directly impacts the accuracy of the diagnosis. Traditional manual evaluation methods rely on the observation of pathologist under microscopes. These methods exhibit high subjectivity, high cost, long duration, and low reliability. With the development of computer-aided diagnosis (CAD), an automated quality assessment system that performs at the level of a professional pathologist is necessary. To address this need, we propose a fully automated quality assessment method for Cervical Cytopathology Whole Slide Images (WSIs) based on The Bethesda System (TBS) diagnostic standards, artificial intelligence algorithms, and the characteristics of clinical data. The method analysis the context of WSIs to quantify quality evaluation metrics which are focused by TBS such as staining quality, cell counts and cell mass proportion through multiple models including object detection, classification and segmentation. Subsequently, the XGBoost model is used to mine the attention paid by pathologists to different quality evaluation metrics when evaluating samples, thereby obtaining a comprehensive WSI sample score calculation model. Experimental results on 100 WSIs demonstrate that the proposed evaluation method has significant advantages in terms of speed and consistency.

病理分析AI辅助图像评估

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