arXiv:2505.13911eess.IVcs.AI2025-05被引 1

利用解剖结构指导弱监督学习,实现肺段精准分割。

Bronchovascular Tree-Guided Weakly Supervised Learning Method for Pulmonary Segment Segmentation

  • 基于支气管血管树结构设计分层监督机制
  • 仅需片段级标签,无需体素级标注,分割精度高
  • 适合缺乏精细标注的医学图像分割任务

肺段分割对癌症定位和手术规划至关重要,但其边界在医学图像中难以区分,像素级标注耗时费力。为此,我们提出一种弱监督学习方法——解剖层级监督学习(AHSL),该方法依据临床解剖定义,利用支气管血管树(动脉、气道、静脉)的精确结构信息进行肺段分割。损失函数设计遵循两个原则:一是使用片段级标签直接监督肺段输出,确保其准确包含对应支气管血管树;二是通过肺叶级监督间接约束肺段,保证其位于正确肺叶内。此外,引入两阶段分割策略融合支气管血管先验信息,并设计一致性损失以增强分割边界平滑性,同时提出新评估指标量化边界光滑度。在私有数据集上的实验结果表明,该方法在无需体素级标注的情况下,仍能实现优异性能。

原文摘要 · Abstract (English)

Pulmonary segment segmentation is crucial for cancer localization and surgical planning. However, the pixel-wise annotation of pulmonary segments is laborious, as the boundaries between segments are indistinguishable in medical images. To this end, we propose a weakly supervised learning (WSL) method, termed Anatomy-Hierarchy Supervised Learning (AHSL), which consults the precise clinical anatomical definition of pulmonary segments to perform pulmonary segment segmentation. Since pulmonary segments reside within the lobes and are determined by the bronchovascular tree, i.e., artery, airway and vein, the design of the loss function is founded on two principles. First, segment-level labels are utilized to directly supervise the output of the pulmonary segments, ensuring that they accurately encompass the appropriate bronchovascular tree. Second, lobe-level supervision indirectly oversees the pulmonary segment, ensuring their inclusion within the corresponding lobe. Besides, we introduce a two-stage segmentation strategy that incorporates bronchovascular priori information. Furthermore, a consistency loss is proposed to enhance the smoothness of segment boundaries, along with an evaluation metric designed to measure the smoothness of pulmonary segment boundaries. Visual inspection and evaluation metrics from experiments conducted on a private dataset demonstrate the effectiveness of our method.

肺段分割弱监督学习解剖先验医学图像

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