用深度集成模型自动测量产程超声图像中的胎儿头位参数,提升评估可靠性。
Automated Fetal Biometry Assessment with Deep Ensembles using Sparse-Sampling of 2D Intrapartum Ultrasound Images
- 通过稀疏采样和集成学习减少数据偏差,精准识别标准切面
- 分割胎儿头骨与耻骨联合,计算角度与距离误差分别仅8.9°和14.35mm
- 适合产科临床辅助决策,尤其在缺乏经验医生时提升一致性
国际超声妇产学会倡导使用产程超声(ISUOG)监测分娩进展,通过胎儿头位变化判断。两个关键参数为角度进展(AoP)和头-耻骨间距(HSD),用于预测器械助产结局。本文参与2024年产程超声挑战赛,提出自动化胎儿生物测量流程,包含三步:(i)从超声视频中分类标准切面;(ii)分割胎儿头骨与耻骨联合;(iii)计算AoP与HSD。采用稀疏采样缓解类别不平衡,用集成深度学习增强不同设备下的泛化能力。第三阶段保留最大连通区域并椭圆拟合分割结果以提高结构保真度。在4名患者、224帧的未见测试集上,分类准确率ACC达0.9452,F1为0.9225,AUC为0.983,MCC为0.8361;分割指标DSC为0.918,平均表面距离ASD为5.71,豪斯多夫距离HD为19.73;角度差Δ_AoP为8.90°,距离差Δ_HSD为14.35mm。该方法有助于理解产程阻滞原因,推动临床风险分层工具发展。
原文摘要 · Abstract (English)
The International Society of Ultrasound advocates Intrapartum Ultrasound (US) Imaging in Obstetrics and Gynecology (ISUOG) to monitor labour progression through changes in fetal head position. Two reliable ultrasound-derived parameters that are used to predict outcomes of instrumental vaginal delivery are the angle of progression (AoP) and head-symphysis distance (HSD). In this work, as part of the Intrapartum Ultrasounds Grand Challenge (IUGC) 2024, we propose an automated fetal biometry measurement pipeline to reduce intra- and inter-observer variability and improve measurement reliability. Our pipeline consists of three key tasks: (i) classification of standard planes (SP) from US videos, (ii) segmentation of fetal head and pubic symphysis from the detected SPs, and (iii) computation of the AoP and HSD from the segmented regions. We perform sparse sampling to mitigate class imbalances and reduce spurious correlations in task (i), and utilize ensemble-based deep learning methods for task (i) and (ii) to enhance generalizability under different US acquisition settings. Finally, to promote robustness in task iii) with respect to the structural fidelity of measurements, we retain the largest connected components and apply ellipse fitting to the segmentations. Our solution achieved ACC: 0.9452, F1: 0.9225, AUC: 0.983, MCC: 0.8361, DSC: 0.918, HD: 19.73, ASD: 5.71, $Δ_{AoP}$: 8.90 and $Δ_{HSD}$: 14.35 across an unseen hold-out set of 4 patients and 224 US frames. The results from the proposed automated pipeline can improve the understanding of labour arrest causes and guide the development of clinical risk stratification tools for efficient and effective prenatal care.
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