构建大规模脑动脉瘤多模态数据集,助力血流模拟与风险预测
Aneumo: A Large-Scale Multimodal Aneurysm Dataset with Computational Fluid Dynamics Simulations and Deep Learning Benchmarks
- 基于427个真实病灶生成10660个3D形态,模拟动脉瘤演化过程
- 在8种血流条件下完成85280组流体动力学仿真,覆盖关键参数
- 含分割掩码支持多模态学习,适合医疗影像与生物流体力学研究
颅内动脉瘤(IAs)是约5%人群中存在的严重脑血管病变,破裂可导致高死亡率。现有风险评估方法主要依赖形态和患者特异性因素,但血流动力学对动脉瘤发展和破裂的影响仍不明确。传统计算流体动力学(CFD)虽准确但计算成本高,难以用于大规模或实时临床场景。为此,我们构建了一个大规模、高保真的动脉瘤CFD数据集,以推动高效机器学习算法的发展。基于427个真实动脉瘤几何结构,通过受控变形生成10660个3D形状,经神经外科医生验证其真实性。每个形状在8种稳态质量流量条件下进行CFD计算,共产生85280组血流动力学数据,涵盖关键参数。此外,数据集包含分割掩码,可支持图像、点云等多模态输入任务。我们还引入基准测试,用于评估当前流场参数估计方法。该数据集旨在推动动脉瘤研究,促进生物流体、生物医学工程及临床风险评估中的数据驱动方法。代码与数据集可在 https://github.com/Xigui-Li/Aneumo 获取。
原文摘要 · Abstract (English)
Intracranial aneurysms (IAs) are serious cerebrovascular lesions found in approximately 5\% of the general population. Their rupture may lead to high mortality. Current methods for assessing IA risk focus on morphological and patient-specific factors, but the hemodynamic influences on IA development and rupture remain unclear. While accurate for hemodynamic studies, conventional computational fluid dynamics (CFD) methods are computationally intensive, hindering their deployment in large-scale or real-time clinical applications. To address this challenge, we curated a large-scale, high-fidelity aneurysm CFD dataset to facilitate the development of efficient machine learning algorithms for such applications. Based on 427 real aneurysm geometries, we synthesized 10,660 3D shapes via controlled deformation to simulate aneurysm evolution. The authenticity of these synthetic shapes was confirmed by neurosurgeons. CFD computations were performed on each shape under eight steady-state mass flow conditions, generating a total of 85,280 blood flow dynamics data covering key parameters. Furthermore, the dataset includes segmentation masks, which can support tasks that use images, point clouds or other multimodal data as input. Additionally, we introduced a benchmark for estimating flow parameters to assess current modeling methods. This dataset aims to advance aneurysm research and promote data-driven approaches in biofluids, biomedical engineering, and clinical risk assessment. The code and dataset are available at: https://github.com/Xigui-Li/Aneumo.
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