为医疗联邦学习设计动态信誉机制,提升生存分析模型稳定性。
Enhancing Federated Survival Analysis through Peer-Driven Client Reputation in Healthcare
- 用同行评分+聚类降噪的混合通信模型,动态评估客户端信誉。
- 在SEER等数据集上C指数稳定高于基线,噪声更新被有效抑制。
- 兼顾隐私保护与模型精度,适合医疗多中心协作场景。
联邦学习(FL)在数字健康领域前景广阔,可在不泄露患者隐私的前提下实现协作建模。然而,机构间数据异质性、缺乏持续信誉机制以及不可靠贡献仍是主要挑战。本文提出一种鲁棒的同行驱动信誉机制,采用混合通信模型,结合去中心化同行反馈与基于聚类的噪声处理,以增强模型聚合效果。关键创新在于将联邦聚合与信誉机制解耦:客户端在共享模型更新前应用差分隐私进行保护,确保信誉计算时敏感信息不外泄;同时未加密的原始更新仍传至服务器用于全局训练。基于多节点的Cox比例风险模型进行生存分析,本框架通过局部性能提升(以风险排序一致性指数,C-index衡量)动态调整信任度,有效缓解数据异质性与信誉缺失问题。在合成数据集及SEER数据集上的实验表明,该方法始终维持高且稳定的C-index值,显著降低噪声更新影响,优于无信誉系统的传统联邦学习方法。
原文摘要 · Abstract (English)
Federated Learning (FL) holds great promise for digital health by enabling collaborative model training without compromising patient data privacy. However, heterogeneity across institutions, lack of sustained reputation, and unreliable contributions remain major challenges. In this paper, we propose a robust, peer-driven reputation mechanism for federated healthcare that employs a hybrid communication model to integrate decentralized peer feedback with clustering-based noise handling to enhance model aggregation. Crucially, our approach decouples the federated aggregation and reputation mechanisms by applying differential privacy to client-side model updates before sharing them for peer evaluation. This ensures sensitive information remains protected during reputation computation, while unaltered updates are sent to the server for global model training. Using the Cox Proportional Hazards model for survival analysis across multiple federated nodes, our framework addresses both data heterogeneity and reputation deficit by dynamically adjusting trust scores based on local performance improvements measured via the concordance index. Experimental evaluations on both synthetic datasets and the SEER dataset demonstrate that our method consistently achieves high and stable C-index values, effectively down-weighing noisy client updates and outperforming FL methods that lack a reputation system.
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