提出两种新方法,用更少辐射剂量实现更高清动态器官成像。
Analytical Reconstruction of Periodically Deformed Objects in Time-resolved CT
- 基于相位分组的解析重建,利用跨阶段投影相关性提升效率
- 实验显示噪声降低且边缘清晰,等效质量下辐射剂量更低
- 适合需要低剂量高精度动态成像的研究者,如生物医学成像
时间分辨计算机断层扫描(Time-resolved CT)广泛用于观测心脏、肺部或听觉结构等周期性变化的动态物体。传统门控法将投影按运动相位分组,在每组内假设物体静止并进行重建,但仅使用各组内部分投影,忽略组间相关性,导致辐射剂量利用率低。本文提出两种解析重建流程,并通过同步辐射显微断层扫描实验数据验证。结果表明,所提方法显著降低重建图像中的随机噪声,同时保持物体锐利特征不变;在相同重建质量下,可实现更低辐射剂量。代码已开源于 github.com/PeriodRecon。
原文摘要 · Abstract (English)
Time-resolved CT is an advanced measurement technique that has been widely used to observe dynamic objects, including periodically varying structures such as hearts, lungs, or hearing structures. To reconstruct these objects from CT projections, a common approach is to divide the projections into several collections based on their motion phases and perform reconstruction within each collection, assuming they originate from a static object. This describes the gating-based method, which is the standard approach for time-periodic reconstruction. However, the gating-based reconstruction algorithm only utilizes a limited subset of projections within each collection and ignores the correlation between different collections, leading to inefficient use of the radiation dose. To address this issue, we propose two analytical reconstruction pipelines in this paper, and validate them with experimental data captured using tomographic synchrotron microscopy. We demonstrate that our approaches significantly reduce random noise in the reconstructed images without blurring the sharp features of the observed objects. Equivalently, our methods can achieve the same reconstruction quality as gating-based methods but with a lower radiation dose. Our code is available at github.com/PeriodRecon.
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