从频域角度重构脑肿瘤分割,提升增强区域识别精度。
Rethinking Brain Tumor Segmentation from the Frequency Domain Perspective
- 通过频域分解分离图像的低频轮廓与高频纹理细节
- 在四个数据集上增强区域分割Dice提升最高达7.72%
- 适合医学影像分析、脑肿瘤诊断及算法优化研究者
精确分割脑肿瘤,特别是对比增强MRI中可见的强化区域(由对比剂注射后显影),对临床诊断和治疗规划至关重要,但当前方法在分割这些区域时表现不佳,主要因未能充分考虑磁共振成像特有的复杂纹理和方向变化。为此,我们提出谐波频域融合网络(HFF-Net),从频域视角重新思考脑肿瘤分割。设计频域分解(FDD)模块,将MRI图像分解为低频成分(捕捉平滑肿瘤轮廓)和高频成分(突出细节纹理与方向边缘)。引入自适应拉普拉斯卷积(ALC)模块,利用动态更新的卷积核自适应强调关键高频特征。设计频域交叉注意力(FDCA)模块,融合语义、位置及切片特异性信息以实现多尺度特征融合。通过可视化、理论推导与实验验证频域改进效果。在四个公开数据集上的大量实验表明,HFF-Net在三个主要子区域的平均Dice得分相对提升4.48%(范围2.39%~7.72%),在对比增强肿瘤区域的分割平均相对提升7.33%(范围5.96%~8.64%),同时保持良好的计算效率与临床可用性。代码:https://github.com/VinyehShaw/HFF。
原文摘要 · Abstract (English)
Precise segmentation of brain tumors, particularly contrast-enhancing regions visible in post-contrast MRI (areas highlighted by contrast agent injection), is crucial for accurate clinical diagnosis and treatment planning but remains challenging. However, current methods exhibit notable performance degradation in segmenting these enhancing brain tumor areas, largely due to insufficient consideration of MRI-specific tumor features such as complex textures and directional variations. To address this, we propose the Harmonized Frequency Fusion Network (HFF-Net), which rethinks brain tumor segmentation from a frequency-domain perspective. To comprehensively characterize tumor regions, we develop a Frequency Domain Decomposition (FDD) module that separates MRI images into low-frequency components, capturing smooth tumor contours and high-frequency components, highlighting detailed textures and directional edges. To further enhance sensitivity to tumor boundaries, we introduce an Adaptive Laplacian Convolution (ALC) module that adaptively emphasizes critical high-frequency details using dynamically updated convolution kernels. To effectively fuse tumor features across multiple scales, we design a Frequency Domain Cross-Attention (FDCA) integrating semantic, positional, and slice-specific information. We further validate and interpret frequency-domain improvements through visualization, theoretical reasoning, and experimental analyses. Extensive experiments on four public datasets demonstrate that HFF-Net achieves an average relative improvement of 4.48\% (ranging from 2.39\% to 7.72\%) in the mean Dice scores across the three major subregions, and an average relative improvement of 7.33% (ranging from 5.96% to 8.64%) in the segmentation of contrast-enhancing tumor regions, while maintaining favorable computational efficiency and clinical applicability. Code: https://github.com/VinyehShaw/HFF.
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