arXiv:2506.13222cs.AIcs.LG2025-06被引 1

用神经动力学模型提升脑电图分析的准确性和泛化能力

NeuroPhysNet: A FitzHugh-Nagumo-Based Physics-Informed Neural Network Framework for Electroencephalograph (EEG) Analysis and Motor Imagery Classification

  • 结合菲茨休-纳古姆模型的物理约束神经网络
  • 在少量数据和跨被试场景下表现更优
  • 适合临床脑疾病诊断与神经康复应用

脑电图(EEG)因其无创性和高时间分辨率,广泛应用于医学诊断和脑机接口(BCI)中。然而,脑电信号常受噪声、非平稳性和被试间差异影响,限制了其临床应用。传统神经网络缺乏生物物理先验知识,导致可解释性差、鲁棒性不足。为此,本文提出NeuroPhysNet,一种基于菲茨休-纳古姆(FitzHugh-Nagumo)模型的物理信息神经网络(PINN)框架,用于脑电信号分析与运动想象分类。该框架嵌入神经动力学原理以约束预测,增强模型鲁棒性。在BCIC-IV-2a数据集上的评估显示,相比传统方法,NeuroPhysNet在数据有限和跨被试场景下均取得更优的准确率与泛化能力,适用于临床环境。通过融合生物物理知识与数据驱动方法,该框架不仅推动了脑机接口发展,也为运动障碍评估和神经康复规划等临床应用提供了更高精度与可靠性的支持。

原文摘要 · Abstract (English)

Electroencephalography (EEG) is extensively employed in medical diagnostics and brain-computer interface (BCI) applications due to its non-invasive nature and high temporal resolution. However, EEG analysis faces significant challenges, including noise, nonstationarity, and inter-subject variability, which hinder its clinical utility. Traditional neural networks often lack integration with biophysical knowledge, limiting their interpretability, robustness, and potential for medical translation. To address these limitations, this study introduces NeuroPhysNet, a novel Physics-Informed Neural Network (PINN) framework tailored for EEG signal analysis and motor imagery classification in medical contexts. NeuroPhysNet incorporates the FitzHugh-Nagumo model, embedding neurodynamical principles to constrain predictions and enhance model robustness. Evaluated on the BCIC-IV-2a dataset, the framework achieved superior accuracy and generalization compared to conventional methods, especially in data-limited and cross-subject scenarios, which are common in clinical settings. By effectively integrating biophysical insights with data-driven techniques, NeuroPhysNet not only advances BCI applications but also holds significant promise for enhancing the precision and reliability of clinical diagnostics, such as motor disorder assessments and neurorehabilitation planning.

脑电分析物理信息网络运动想象神经康复

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