综述垂体及垂体瘤自动分割技术,评估深度学习效果与局限。
Systematic Review of Pituitary Gland and Pituitary Adenoma Automatic Segmentation Techniques in Magnetic Resonance Imaging
- 基于U-Net的深度学习方法为主流,部分实现高精度分割
- 腺瘤分割Dice最高达96.41%,正常垂体仅0.19%-89.00%
- 小结构分割仍不稳,需更大更多样数据集支持临床应用
准确分割磁共振成像(MRI)中的垂体及垂体瘤对诊断和治疗至关重要。本系统综述评估了34项自动与半自动分割方法,总结其技术路线与性能指标(如Dice重叠系数)。多数研究采用深度学习,以U-Net模型最为常见。自动方法在垂体分割上取得Dice分数0.19%–89.00%,腺瘤分割为4.60%–96.41%;半自动方法表现更优,垂体为80.00%–92.10%,腺瘤为75.90%–88.36%。然而多数研究未报告磁场强度、患者年龄及腺瘤大小等关键信息。尽管基于U-Net的自动化技术在腺瘤分割中展现出潜力,但对微小正常垂体结构仍难以保持稳定性能。未来需更多创新与大规模、多样化的数据集,以提升临床实用性。
原文摘要 · Abstract (English)
Purpose: Accurate segmentation of both the pituitary gland and adenomas from magnetic resonance imaging (MRI) is essential for diagnosis and treatment of pituitary adenomas. This systematic review evaluates automatic segmentation methods for improving the accuracy and efficiency of MRI-based segmentation of pituitary adenomas and the gland itself. Methods: We reviewed 34 studies that employed automatic and semi-automatic segmentation methods. We extracted and synthesized data on segmentation techniques and performance metrics (such as Dice overlap scores). Results: The majority of reviewed studies utilized deep learning approaches, with U-Net-based models being the most prevalent. Automatic methods yielded Dice scores of 0.19--89.00\% for pituitary gland and 4.60--96.41\% for adenoma segmentation. Semi-automatic methods reported 80.00--92.10\% for pituitary gland and 75.90--88.36\% for adenoma segmentation. Conclusion: Most studies did not report important metrics such as MR field strength, age and adenoma size. Automated segmentation techniques such as U-Net-based models show promise, especially for adenoma segmentation, but further improvements are needed to achieve consistently good performance in small structures like the normal pituitary gland. Continued innovation and larger, diverse datasets are likely critical to enhancing clinical applicability.
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