arXiv:2507.00660eess.IVcs.AI2025-07中稿 · MICCAI 2025被引 1

用稀疏标注实现4D超声瓣膜精准分割,提升时序一致性

MTCNet: Motion and Topology Consistency Guided Learning for Mitral Valve Segmentationin 4D Ultrasound

  • 通过双向注意力记忆库传递时空特征,实现跨相位一致性学习
  • 在160例患者1408个相位上达到87.3%的Dice分数和1.75mm的HD值
  • 融合解剖先验知识,适合医疗影像中结构连续性分析场景

二尖瓣反流是常见心脏疾病。四维(4D)超声已成为评估动态瓣膜形态的主要成像方式。然而,由于相位标注稀疏、运动伪影严重及图像质量差,4D二尖瓣(MV)分析仍具挑战性。现有方法缺乏相位间依赖关系建模,限制了分析效果。为此,我们提出一种运动-拓扑一致性引导网络(MTCNet),用于半监督学习下的4D MV超声分割。MTCNet仅需稀疏的收缩末期与舒张末期标注。首先,设计跨相位运动引导的一致性学习策略,利用双向注意力记忆库传播时空特征,实现单相与跨相位优异性能。其次,提出新颖的拓扑引导相关正则化,融入解剖学先验,保持形态合理性。因此,MTCNet能有效利用标记与未标记相位间的结构对应关系。在首个大规模4D MV数据集(160名患者共1408个相位)上的广泛评估显示,其跨相位一致性优于其他先进方法(Dice: 87.30%,HD: 1.75mm)。代码与数据集已公开于https://github.com/crs524/MTCNet。

原文摘要 · Abstract (English)

Mitral regurgitation is one of the most prevalent cardiac disorders. Four-dimensional (4D) ultrasound has emerged as the primary imaging modality for assessing dynamic valvular morphology. However, 4D mitral valve (MV) analysis remains challenging due to limited phase annotations, severe motion artifacts, and poor imaging quality. Yet, the absence of inter-phase dependency in existing methods hinders 4D MV analysis. To bridge this gap, we propose a Motion-Topology guided consistency network (MTCNet) for accurate 4D MV ultrasound segmentation in semi-supervised learning (SSL). MTCNet requires only sparse end-diastolic and end-systolic annotations. First, we design a cross-phase motion-guided consistency learning strategy, utilizing a bi-directional attention memory bank to propagate spatio-temporal features. This enables MTCNet to achieve excellent performance both per- and inter-phase. Second, we devise a novel topology-guided correlation regularization that explores physical prior knowledge to maintain anatomically plausible. Therefore, MTCNet can effectively leverage structural correspondence between labeled and unlabeled phases. Extensive evaluations on the first largest 4D MV dataset, with 1408 phases from 160 patients, show that MTCNet performs superior cross-phase consistency compared to other advanced methods (Dice: 87.30%, HD: 1.75mm). Both the code and the dataset are available at https://github.com/crs524/MTCNet.

医学影像4D超声分割半监督

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