arXiv:2507.03295cs.CV2025-07

用扩散模型+临床知识约束,提升内镜手术阶段识别准确率。

CPKD: Clinical Prior Knowledge-Constrained Diffusion Models for Surgical Phase Recognition in Endoscopic Submucosal Dissection

  • 基于扩散模型生成阶段序列,逐步去噪重建
  • 在ESD820等数据集上达到领先或相当性能
  • 融合临床先验知识纠正逻辑错误,适合医疗场景

胃肠道恶性肿瘤是全球癌症死亡的主要原因,晚期预后仍极差。内镜黏膜下剥离术(Endoscopic Submucosal Dissection, ESD)作为早期胃癌治疗的突破性技术,已发展为应对多种胃肠道病变的通用手段。尽管计算机辅助系统显著提升了操作精度与安全性,但其临床应用面临关键瓶颈:复杂内镜流程中可靠的手术阶段识别。现有先进方法多依赖多阶段精炼架构,迭代优化时间预测。本文提出临床先验知识约束的扩散模型(Clinical Prior Knowledge-Constrained Diffusion, CPKD),通过去噪扩散原理重构阶段序列,同时保留迭代精炼思想。该模型从随机噪声开始,基于视觉-时序特征逐步重建阶段序列。为捕捉位置先验、边界模糊性与关系依赖三类领域特性,设计条件掩码策略;并引入临床先验知识进行训练,增强纠错能力。在ESD820、Cholec80及外部多中心数据集上的全面评估表明,CPKD性能优于或相当于当前最优方法,验证了基于扩散的生成范式在手术阶段识别中的有效性。

原文摘要 · Abstract (English)

Gastrointestinal malignancies constitute a leading cause of cancer-related mortality worldwide, with advanced-stage prognosis remaining particularly dismal. Originating as a groundbreaking technique for early gastric cancer treatment, Endoscopic Submucosal Dissection has evolved into a versatile intervention for diverse gastrointestinal lesions. While computer-assisted systems significantly enhance procedural precision and safety in ESD, their clinical adoption faces a critical bottleneck: reliable surgical phase recognition within complex endoscopic workflows. Current state-of-the-art approaches predominantly rely on multi-stage refinement architectures that iteratively optimize temporal predictions. In this paper, we present Clinical Prior Knowledge-Constrained Diffusion (CPKD), a novel generative framework that reimagines phase recognition through denoising diffusion principles while preserving the core iterative refinement philosophy. This architecture progressively reconstructs phase sequences starting from random noise and conditioned on visual-temporal features. To better capture three domain-specific characteristics, including positional priors, boundary ambiguity, and relation dependency, we design a conditional masking strategy. Furthermore, we incorporate clinical prior knowledge into the model training to improve its ability to correct phase logical errors. Comprehensive evaluations on ESD820, Cholec80, and external multi-center demonstrate that our proposed CPKD achieves superior or comparable performance to state-of-the-art approaches, validating the effectiveness of diffusion-based generative paradigms for surgical phase recognition.

手术阶段识别扩散模型临床先验内镜手术

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