arXiv:2507.08050cs.LGcs.AI2025-07被引 1

解决医疗数据少且隐私难保的难题,实现跨机构呼吸病精准诊断。

An Enhanced Privacy-preserving Federated Few-shot Learning Framework for Respiratory Disease Diagnosis

  • 用元随机梯度法缓解小样本过拟合问题。
  • 加高斯差分隐私噪声,防止模型泄露病人图像。
  • 加权平均聚合本地模型,适配不同医院数据分布。

医学数据标注成本高,导致资源受限环境下高质量标注数据稀缺。患者隐私担忧使机构间直接共享本地医疗数据变得困难,现有依赖大量数据的集中式方法常牺牲隐私。本文提出一种具有隐私保护机制的联邦少样本学习框架,用于呼吸系统疾病诊断。提出元随机梯度下降算法,缓解传统梯度下降在数据不足时的过拟合问题;为防止梯度泄露,在本地模型训练中引入标准高斯分布的差分隐私噪声,避免医疗图像被重建;鉴于呼吸病数据分散于各医疗机构,采用加权平均算法聚合各客户端本地诊断模型,提升模型在不同结构、类别和分布数据上的适应性。实验表明,该方法在引入差分隐私的前提下,仍能有效诊断不同来源的呼吸系统疾病数据。

原文摘要 · Abstract (English)

The labor-intensive nature of medical data annotation presents a significant challenge for respiratory disease diagnosis, resulting in a scarcity of high-quality labeled datasets in resource-constrained settings. Moreover, patient privacy concerns complicate the direct sharing of local medical data across institutions, and existing centralized data-driven approaches, which rely on amounts of available data, often compromise data privacy. This study proposes a federated few-shot learning framework with privacy-preserving mechanisms to address the issues of limited labeled data and privacy protection in diagnosing respiratory diseases. In particular, a meta-stochastic gradient descent algorithm is proposed to mitigate the overfitting problem that arises from insufficient data when employing traditional gradient descent methods for neural network training. Furthermore, to ensure data privacy against gradient leakage, differential privacy noise from a standard Gaussian distribution is integrated into the gradients during the training of private models with local data, thereby preventing the reconstruction of medical images. Given the impracticality of centralizing respiratory disease data dispersed across various medical institutions, a weighted average algorithm is employed to aggregate local diagnostic models from different clients, enhancing the adaptability of a model across diverse scenarios. Experimental results show that the proposed method yields compelling results with the implementation of differential privacy, while effectively diagnosing respiratory diseases using data from different structures, categories, and distributions.

联邦学习少样本隐私保护呼吸病诊断

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