arXiv:2507.08402q-bio.NCcs.LG2025-07NeurIPS被引 4

新模型SPINT无需标记就能跨会话稳定解码神经信号,适合长期脑机接口使用。

SPINT: Spatial Permutation-Invariant Neural Transformer for Consistent Intracortical Motor Decoding

  • 用动态位置嵌入处理无序神经单元,自动识别单元身份
  • 在三个数据集上超越现有零样本和少样本方法,无需测试时调参
  • 支持少量无标签数据快速适应,适合临床长期应用

皮层内脑机接口(iBCI)旨在从神经群体活动中解码行为,帮助运动障碍者恢复运动与交流能力。长期使用中,神经记录的非平稳性导致记录群体组成和调制特性随会话变化,现有方法依赖固定神经单元身份,需测试时标签或参数更新,限制泛化性并增加部署负担。本文提出SPINT——一种空间排列不变的神经变换器框架,直接处理无序神经单元集合。核心是上下文相关的动态位置嵌入,可推断单元身份,实现跨会话灵活泛化。SPINT支持可变大小群体推理,并利用少量测试会话无标签数据实现无梯度、少样本适应。为增强对群体变异的鲁棒性,引入动态通道丢弃作为iBCI专用正则化方法,模拟训练中群体组成变化。在FALCON基准的三个多会话数据集上评估,涵盖人类与非人灵长类连续运动解码任务。SPINT展现强跨会话泛化能力,优于现有零样本与少样本无监督基线,且无需测试时对齐或微调。本工作为长期iBCI应用提供了稳健可扩展的解码框架初探。

原文摘要 · Abstract (English)

Intracortical Brain-Computer Interfaces (iBCI) aim to decode behavior from neural population activity, enabling individuals with motor impairments to regain motor functions and communication abilities. A key challenge in long-term iBCI is the nonstationarity of neural recordings, where the composition and tuning profiles of the recorded populations are unstable across recording sessions. Existing methods attempt to address this issue by explicit alignment techniques; however, they rely on fixed neural identities and require test-time labels or parameter updates, limiting their generalization across sessions and imposing additional computational burden during deployment. In this work, we introduce SPINT - a Spatial Permutation-Invariant Neural Transformer framework for behavioral decoding that operates directly on unordered sets of neural units. Central to our approach is a novel context-dependent positional embedding scheme that dynamically infers unit-specific identities, enabling flexible generalization across recording sessions. SPINT supports inference on variable-size populations and allows few-shot, gradient-free adaptation using a small amount of unlabeled data from the test session. To further promote model robustness to population variability, we introduce dynamic channel dropout, a regularization method for iBCI that simulates shifts in population composition during training. We evaluate SPINT on three multi-session datasets from the FALCON Benchmark, covering continuous motor decoding tasks in human and non-human primates. SPINT demonstrates robust cross-session generalization, outperforming existing zero-shot and few-shot unsupervised baselines while eliminating the need for test-time alignment and fine-tuning. Our work contributes an initial step toward a robust and scalable neural decoding framework for long-term iBCI applications.

脑机接口神经解码时空建模少样本学习

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