arXiv:2507.14308eess.IVcs.CV2025-07被引 4

自监督模型同时重建与去噪低场肺部MRI,提升图像清晰度并减半扫描时间。

Self-Supervised Joint Reconstruction and Denoising of T2-Weighted PROPELLER MRI of the Lungs at 0.55T

  • 将PROPELLER数据分成两部分,自监督训练实现无干净标签的联合重建与去噪
  • 图像清晰度显著提升,与CT对齐良好,且只需原一半扫描刀数
  • 适合低场MRI、资源受限场景,尤其对新冠后肺部影像研究有价值

本研究旨在通过自监督联合重建与去噪模型提升0.55T T2加权PROPELLER肺部MRI质量。使用44例既往新冠感染患者的T2加权0.55T肺部MRI数据集。构建自监督学习框架,将PROPELLER每一刀沿读出方向分为两个子集:一个用于训练非迭代重建网络,另一个用于损失计算,实现无需干净真值的自监督训练,并利用匹配噪声统计特性进行去噪。作为对比,采用马钦科-帕斯图尔主成分分析(MPPCA)沿线圈维度处理后进行传统并行成像重建。由两名经验放射科医师独立进行图像质量视觉评估。结果表明,所提方法显著改善了肺部图像的清晰度和结构完整性;对于有对应CT的病例,重建图像与CT高度匹配。此外,该模型可将扫描刀数减半。读者评估显示,所提方法在所有评价维度上均显著优于MPPCA去噪图像(Wilcoxon符号秩检验,p<0.001),存在中等程度阅片者间一致性(加权Cohen's kappa=0.55;精确及±1分一致率91%)。结论:通过利用k空间子集间内在结构冗余性,该自监督学习模型有效实现了0.55T T2加权肺部MRI(PROPELLER采样)的图像重建与噪声抑制。

原文摘要 · Abstract (English)

Purpose: This study aims to improve 0.55T T2-weighted PROPELLER lung MRI through a self-supervised joint reconstruction and denoising model. Methods: T2-weighted 0.55T lung MRI dataset including 44 patients with previous covid infection were used. A self-supervised learning framework was developed, where each blade of the PROPELLER acquisition was split along the readout direction into two partitions. One subset trains the unrolled reconstruction network, while the other subset is used for loss calculation, enabling self-supervised training without clean targets and leveraging matched noise statistics for denoising. For comparison, Marchenko-Pastur Principal Component Analysis (MPPCA) was performed along the coil dimension, followed by conventional parallel imaging reconstruction. The quality of the reconstructed lung MRI was assessed visually by two experienced radiologists independently. Results: The proposed self-supervised model improved the clarity and structural integrity of the lung images. For cases with available CT scans, the reconstructed images demonstrated strong alignment with corresponding CT images. Additionally, the proposed model enables further scan time reduction by requiring only half the number of blades. Reader evaluations confirmed that the proposed method outperformed MPPCA-denoised images across all categories (Wilcoxon signed-rank test, p<0.001), with moderate inter-reader agreement (weighted Cohen's kappa=0.55; percentage of exact and within +/-1 point agreement=91%). Conclusion: By leveraging intrinsic structural redundancies between two disjoint splits of k-space subsets, the proposed self-supervised learning model effectively reconstructs the image while suppressing the noise for 0.55T T2-weighted lung MRI with PROPELLER sampling.

MRI重建自监督学习低场成像肺部影像

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