用标签树结构损失提升复杂医学图像分割精度
Label tree semantic losses for rich multi-class medical image segmentation
- 基于标签层级关系设计语义损失函数
- 在全监督与稀疏标注任务中均显著提效
- 适合需区分细微类别的医学影像分析场景
精准的医学图像分割将推动下一代AI临床实践,用于术前规划、术中导航和术后评估。但传统方法对所有误分类惩罚一致,忽略标签间的语义关系,尤其在标签种类丰富时问题突出。本文提出两种基于标签树结构的语义损失函数,利用标签的层次组织关系,并结合最近提出的稀疏、无背景标注训练方法,扩展损失函数的应用范围。在头颅MRI全脑分区(全监督)和神经外科高光谱成像场景理解(稀疏标注)两个任务上进行大量实验。结果表明,在全脑分割任务中,基于Wasserstein的复合损失表现最优;在稀疏高光谱成像任务中,层级加权顶层监督效果最佳,均优于对比基线。
原文摘要 · Abstract (English)
Rich and accurate medical image segmentation is poised to underpin the next generation of AI-defined clinical practice by delineating critical anatomy for pre-operative planning, guiding real-time intra-operative navigation, and supporting precise post-operative assessment. However, commonly used learning methods for medical and surgical imaging segmentation tasks penalise all errors equivalently and thus fail to exploit any inter-class semantics in the label space. This becomes particularly problematic as the cardinality and richness of labels increases to include subtly different classes. In this work, we propose two tree-based semantic loss functions which take advantage of a hierarchical organisation of the labels. We further incorporate our losses in a recently proposed approach for training with sparse, background-free annotations to extend the applicability of our proposed losses. Extensive experiments are reported on two medical and surgical imaging segmentation tasks, namely head MRI for whole brain parcellation with full supervision and neurosurgical hyperspectral imaging for scene understanding with sparse annotations. Results demonstrate consistent improvements over the evaluated task-specific baselines, with the strongest support for the Wasserstein-based compound loss in whole-brain parcellation and for hierarchy-weighted top-level supervision in the sparse HSI setting.
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