利用患者多期影像先验信息,实现动态MRI加速成像。
Multisession Longitudinal Dynamic MRI Incorporating Patient-Specific Prior Image Information Across Time
- 将多期动态MRI数据拼接为长序列,基于低秩子空间重建
- 相比单期重建,图像质量更优且保持各期差异性
- 适合长期随访的临床动态成像,提升效率与一致性
临床中常进行多次磁共振成像(MRI),各次扫描间共享解剖结构与运动信息。然而现有重建方法独立处理每期数据,未充分利用纵向信息。本文提出一种纵向动态MRI新范式,通过引入患者特异性先验图像,挖掘跨期时间相关性。该框架可随着更多扫描会话的积累,逐步提升数据采集速度并缩短扫描时间。以先进的4D Golden-angle RAdial Sparse Parallel(GRASP)MRI为例,将多期时间分辨4D GRASP数据集拼接为扩展动态序列,采用低秩子空间重建算法。实验表明,纵向4D GRASP重建在图像质量上持续优于标准单期重建,同时保留了各期间的形态变化。该方法对解剖变化、成像间隔和体形差异均表现出强鲁棒性,展示了其在纵向MRI应用中提升成像效率与一致性的潜力。更广泛地,本工作提出了一种情境感知的成像新范式:对患者的观察越多,成像越快。
原文摘要 · Abstract (English)
Serial Magnetic Resonance Imaging (MRI) exams are often performed in clinical practice, offering shared anatomical and motion information across imaging sessions. However, existing reconstruction methods process each session independently without leveraging this valuable longitudinal information. In this work, we propose a novel concept of longitudinal dynamic MRI, which incorporates patient-specific prior images to exploit temporal correlations across sessions. This framework enables progressive acceleration of data acquisition and reduction of scan time as more imaging sessions become available. The concept is demonstrated using the 4D Golden-angle RAdial Sparse Parallel (GRASP) MRI, a state-of-the-art dynamic imaging technique. Longitudinal reconstruction is performed by concatenating multi-session time-resolved 4D GRASP datasets into an extended dynamic series, followed by a low-rank subspace-based reconstruction algorithm. A series of experiments were conducted to evaluate the feasibility and performance of the proposed method. Results show that longitudinal 4D GRASP reconstruction consistently outperforms standard single-session reconstruction in image quality, while preserving inter-session variations. The approach demonstrated robustness to changes in anatomy, imaging intervals, and body contour, highlighting its potential for improving imaging efficiency and consistency in longitudinal MRI applications. More generally, this work suggests a new context-aware imaging paradigm in which the more we see a patient, the faster we can image.
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