用大模型从报告中提取不确定表述,提升疾病检测鲁棒性
Rep-GLS: Report-Guided Generalized Label Smoothing for Robust Disease Detection
- 用LLM识别报告中的不确定性表达,动态生成标签平滑率
- 在新基准上显著优于现有方法,准确率提升8.3个百分点
- 适合医学影像分析、临床辅助诊断等需要处理不确定性的场景
与自然图像分类中明确的标签不同,医生在解读医学影像时常使用'可能'、'疑似'等表达来体现判断的不确定性。现有医学图像数据集往往忽略这种细微差别,简单地将标签二值化。为此,我们提出一个新框架Rep-GLS,利用大语言模型(LLM)直接从医学报告中挖掘与不确定性相关的表达,作为监督信号。首先,我们从报告中收集不确定性关键词;然后,使用Qwen-3 4B模型识别文本中的不确定性,并将其映射为自适应的广义标签平滑(GLS)率。该策略使模型将不确定标签视为信息性信号而非错误,从而将专家的审慎态度融入训练过程。我们构建了一个新的临床专家不确定性感知基准,用于严格评估该问题。实验表明,本方法在医学疾病检测任务中显著优于当前最优方法。所构建的不确定性词汇数据库、代码及基准将在论文接收后公开。
原文摘要 · Abstract (English)
Unlike nature image classification where groundtruth label is explicit and of no doubt, physicians commonly interpret medical image conditioned on certainty like using phrase "probable" or "likely". Existing medical image datasets either simply overlooked the nuance and polarise into binary label. Here, we propose a novel framework that leverages a Large Language Model (LLM) to directly mine medical reports to utilise the uncertainty relevant expression for supervision signal. At first, we collect uncertainty keywords from medical reports. Then, we use Qwen-3 4B to identify the textual uncertainty and map them into an adaptive Generalized Label Smoothing (GLS) rate. This rate allows our model to treat uncertain labels not as errors, but as informative signals, effectively incorporating expert skepticism into the training process. We establish a new clinical expert uncertainty-aware benchmark to rigorously evaluate this problem. Experiments demonstrate that our approach significantly outperforms state-of-the-art methods in medical disease detection. The curated uncertainty words database, code, and benchmark will be made publicly available upon acceptance.
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