通过通道耦合损失提升视网膜动静脉分类精度
Improve Retinal Artery/Vein Classification via Channel Couplin
- 设计通道耦合一致性损失,统一动脉、静脉与血管整体预测
- 在RITE、LES-AV、HRF三数据集上达到最新最优性能
- 适合眼科疾病自动诊断研究者参考
视网膜血管分割在眼底图像分析中至关重要,用于系统性和眼部疾病的诊断。在此基础上,将分割出的血管分类为动脉和静脉(A/V),可提取血管宽度、直径和迂曲度等临床相关特征,对糖尿病和高血压性视网膜病变的检测具有重要意义。然而,人工分割与分类耗时、成本高且结果不一致。尽管卷积神经网络已提出多种自动化方法,但仍存在缺陷:现有方法将动脉、静脉及整体血管分割视为三个独立的二值任务,忽视了这些解剖结构间的内在耦合关系。由于动脉和静脉是整体视网膜血管图的子集,其预测应与整体图保持一致性,因此我们提出一种新的通道耦合血管一致性损失,以强制三者预测的一致性,避免网络偏向于简单的二值分割任务。此外,还引入像素级对比正则化项,以提取更具区分性的细粒度特征表示,实现更准确的视网膜动静脉分类。在RITE、LES-AV和HRF三个公开数据集上均取得当前最优结果。代码将在论文接收后公开。
原文摘要 · Abstract (English)
Retinal vessel segmentation plays a vital role in analyzing fundus images for the diagnosis of systemic and ocular diseases. Building on this, classifying segmented vessels into arteries and veins (A/V) further enables the extraction of clinically relevant features such as vessel width, diameter and tortuosity, which are essential for detecting conditions like diabetic and hypertensive retinopathy. However, manual segmentation and classification are time-consuming, costly and inconsistent. With the advancement of Convolutional Neural Networks, several automated methods have been proposed to address this challenge, but there are still some issues. For example, the existing methods all treat artery, vein and overall vessel segmentation as three separate binary tasks, neglecting the intrinsic coupling relationships between these anatomical structures. Considering artery and vein structures are subsets of the overall retinal vessel map and should naturally exhibit prediction consistency with it, we design a novel loss named Channel-Coupled Vessel Consistency Loss to enforce the coherence and consistency between vessel, artery and vein predictions, avoiding biasing the network toward three simple binary segmentation tasks. Moreover, we also introduce a regularization term named intra-image pixel-level contrastive loss to extract more discriminative feature-level fine-grained representations for accurate retinal A/V classification. SOTA results have been achieved across three public A/V classification datasets including RITE, LES-AV and HRF. Our code will be available upon acceptance.
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