用AI从植物中挖掘材料设计新思路,实测造出可调性能的新型粘合剂。
Generative Artificial Intelligence Extracts Structure-Function Relationships from Plants for New Materials
- 用植物科学与材料工程交叉文献训练AI,自动提炼结构-功能关系。
- 生成数百个可实验的假设,实测制成新型花粉粘合剂,剪切强度可测。
- 适合材料设计、生物启发研究者,推动人机协作创新。
大型语言模型(LLMs)已重塑知识获取与创意生成方式,但在跨学科材料科学等实验领域应用仍有限。本文提出首个整合生成式AI与植物科学、仿生学及材料工程等分散文献的框架,聚焦湿度响应系统如花粉材料和棕榈叶(Rhapis excelsa),实现自驱动与自适应性能。通过微调模型BioinspiredLLM、检索增强生成(RAG)、智能体系统与分层采样策略,提取结构-性能关系,并转化为新型生物启发材料设计。结构化推理协议可从单一查询生成并评估数百个假设,催生可实验的新构想。经实验室验证:由LLM生成的制备流程、材料设计与力学预测成功实现,制得一种可调控形态的新型花粉基粘合剂,其剪切强度可测量,为未来植物衍生粘合剂设计奠定基础。本工作证明了AI辅助创意能驱动真实材料设计,促进有效的人机协作。
原文摘要 · Abstract (English)
Large language models (LLMs) have reshaped the research landscape by enabling new approaches to knowledge retrieval and creative ideation. Yet their application in discipline-specific experimental science, particularly in highly multi-disciplinary domains like materials science, remains limited. We present a first-of-its-kind framework that integrates generative AI with literature from hitherto-unconnected fields such as plant science, biomimetics, and materials engineering to extract insights and design experiments for materials. We focus on humidity-responsive systems such as pollen-based materials and Rhapis excelsa (broadleaf lady palm) leaves, which exhibit self-actuation and adaptive performance. Using a suite of AI tools, including a fine-tuned model (BioinspiredLLM), Retrieval-Augmented Generation (RAG), agentic systems, and a Hierarchical Sampling strategy, we extract structure-property relationships and translate them into new classes of bioinspired materials. Structured inference protocols generate and evaluate hundreds of hypotheses from a single query, surfacing novel and experimentally tractable ideas. We validate our approach through real-world implementation: LLM-generated procedures, materials designs, and mechanical predictions were tested in the laboratory, culminating in the fabrication of a novel pollen-based adhesive with tunable morphology and measured shear strength, establishing a foundation for future plant-derived adhesive design. This work demonstrates how AI-assisted ideation can drive real-world materials design and enable effective human-AI collaboration.
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