arXiv:2508.08916cs.CVcs.LG2025-08

自动分析脑肿瘤术后影像,生成符合临床标准的报告

Automatic and standardized surgical reporting for central nervous system tumors

  • 用注意力U-Net分三类病灶:原发瘤、残留瘤、切除腔
  • 残余瘤分割准确率达66%,分类模型肿瘤类型识别达80%
  • 结果按RANO 2.0标准输出,适合放射科医生和神经外科团队

磁共振成像对中枢神经系统肿瘤的评估至关重要,可指导手术规划、治疗决策及术后效果评价。尽管已有研究推进了术前肿瘤分割与报告生成,但对术后影像分析关注较少。本研究提出一套完整的术后标准化报告流程:采用Attention U-Net对术前非增强瘤体、术后增强残留瘤及切除腔进行分割;利用DenseNet实现序列分类与增强病灶类型识别。模型在2000至7000例多中心数据上训练,5折交叉验证。分割模型在体素层面平均Dice分数分别为:瘤体87%、非增强瘤体66%、增强残留瘤70%、切除腔77%;分类模型在序列分类上达到99.5%平衡准确率,肿瘤类型分类达80%。该流程已集成至开源平台Raidionics,新增术后分析模块,支持符合RANO 2.0指南的自动化分析与报告生成,提升术后评估与临床决策效率。

原文摘要 · Abstract (English)

Magnetic resonance (MR) imaging is essential for evaluating central nervous system (CNS) tumors, guiding surgical planning, treatment decisions, and assessing postoperative outcomes and complication risks. While recent work has advanced automated tumor segmentation and report generation, most efforts have focused on preoperative data, with limited attention to postoperative imaging analysis. This study introduces a comprehensive pipeline for standardized postsurtical reporting in CNS tumors. Using the Attention U-Net architecture, segmentation models were trained for the preoperative (non-enhancing) tumor core, postoperative contrast-enhancing residual tumor, and resection cavity. Additionally, MR sequence classification and tumor type identification for contrast-enhancing lesions were explored using the DenseNet architecture. The models were integrated into a reporting pipeline, following the RANO 2.0 guidelines. Training was conducted on multicentric datasets comprising 2000 to 7000 patients, using a 5-fold cross-validation. Evaluation included patient-, voxel-, and object-wise metrics, with benchmarking against the latest BraTS challenge results. The segmentation models achieved average voxel-wise Dice scores of 87%, 66%, 70%, and 77% for the tumor core, non-enhancing tumor core, contrast-enhancing residual tumor, and resection cavity, respectively. Classification models reached 99.5% balanced accuracy in MR sequence classification and 80% in tumor type classification. The pipeline presented in this study enables robust, automated segmentation, MR sequence classification, and standardized report generation aligned with RANO 2.0 guidelines, enhancing postoperative evaluation and clinical decision-making. The proposed models and methods were integrated into Raidionics, open-source software platform for CNS tumor analysis, now including a dedicated module for postsurgical analysis.

脑肿瘤术后分析自动报告影像分割

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