arXiv:2508.09264cs.LGcs.AI2025-08

用深度学习从脑电信号中精准识别气味存在,准确率超86%。

Detection of Odor Presence via Deep Neural Networks

  • 用一维卷积网络融合多种特征,从嗅球脑电信号中解码气味
  • 在2349次实验中达到86.6%准确率,远超以往基准
  • 适用于神经科学与智能传感交叉研究,适合脑机接口开发者

气味检测在食品安全、环境监测、医学诊断等领域至关重要。当前人工传感器难以处理复杂气味混合物,而非侵入式记录又缺乏可靠的单次试验一致性。本研究提出一种初步方案,验证两个假设:(i) 局部场电位(LFP)的频谱特征足以实现鲁棒的单次试验气味检测;(ii) 仅来自嗅球的信号已足够。为此,我们构建了一个由残差卷积网络(ResCNN)和注意力卷积网络(AttentionCNN)组成的集成模型,从多通道嗅球LFP信号中解码气味是否存在。在7只清醒小鼠的2,349次试验中,最终集成模型支持两个假设,平均准确率达86.6%,F1分数为81.0%,AUC达0.9247,显著优于以往基准。t-SNE可视化显示该框架捕捉到具有生物学意义的特征模式。结果表明,仅通过细胞外LFP即可实现可靠单次气味检测,且深度学习有助于深入理解嗅觉表征。

原文摘要 · Abstract (English)

Odor detection underpins food safety, environmental monitoring, medical diagnostics, and many more fields. The current artificial sensors developed for odor detection struggle with complex mixtures while non-invasive recordings lack reliable single-trial fidelity. To develop a general system for odor detection, in this study we present a preliminary work where we aim to test two hypotheses: (i) that spectral features of local field potentials (LFPs) are sufficient for robust single-trial odor detection and (ii) that signals from the olfactory bulb alone are adequate. To test two hypotheses, we propose an ensemble of complementary one-dimensional convolutional networks (ResCNN and AttentionCNN) that decodes the presence of odor from multichannel olfactory bulb LFPs. Tested on 2,349 trials from seven awake mice, our final ensemble model supports both hypotheses, achieving a mean accuracy of 86.6%, an F1-score of 81.0%, and an AUC of 0.9247, substantially outperforming previous benchmarks. In addition, the t-SNE visualization confirms that our framework captures biologically significant signatures. These findings establish the feasibility of robust single-trial detection of the presence of odor from extracellular LFPs, as well as demonstrate the potential of deep learning models to provide a deeper understanding of olfactory representations.

气味识别脑电信号深度学习神经解码

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