arXiv:2508.12702q-bio.NCcs.AI2025-08

用统一电路模型实现抗噪编码与记忆保持

A Unified Cortical Circuit Model with Divisive Normalization and Self-Excitation for Robust Representation and Memory Maintenance

  • 结合除法归一化与自激发,构建可稳定维持信息的神经环路
  • 在刺激期间实现输入比例化的稳定,刺激消失后仍能自持记忆
  • 适用于抗噪编码与贝叶斯推理任务,适合神经科学与类脑计算研究者

稳健的信息表征及其持久维持是高级认知功能的基础。现有模型分别采用不同神经机制处理抗噪声或信息保持,但缺乏整合二者统一框架——这正是理解皮层计算的关键空白。本文提出一种递归神经环路,将除法归一化与自激发相结合,实现鲁棒编码与稳定记忆。数学分析表明,在适当参数下,系统形成连续吸引子,具备两大特性:(1) 刺激呈现期间输入成比例地稳定;(2) 刺激消失后仍能维持自持记忆状态。模型在两个经典任务中展现通用性:(a) 随机点运动图(RDK)中的抗噪编码;(b) 概率性威斯康星卡片分类测试(pWCST)中的近似贝叶斯信念更新。该工作建立了一个统一的数学框架,将噪声抑制、工作记忆与近似贝叶斯推断整合于单一皮层微环路中,为大脑基本计算提供了新见解,并指导生物合理的人工神经网络设计。

原文摘要 · Abstract (English)

Robust information representation and its persistent maintenance are fundamental for higher cognitive functions. Existing models employ distinct neural mechanisms to separately address noise-resistant processing or information maintenance, yet a unified framework integrating both operations remains elusive -- a critical gap in understanding cortical computation. Here, we introduce a recurrent neural circuit that combines divisive normalization with self-excitation to achieve both robust encoding and stable retention of normalized inputs. Mathematical analysis shows that, for suitable parameter regimes, the system forms a continuous attractor with two key properties: (1) input-proportional stabilization during stimulus presentation; and (2) self-sustained memory states persisting after stimulus offset. We demonstrate the model's versatility in two canonical tasks: (a) noise-robust encoding in a random-dot kinematogram (RDK) paradigm; and (b) approximate Bayesian belief updating in a probabilistic Wisconsin Card Sorting Test (pWCST). This work establishes a unified mathematical framework that bridges noise suppression, working memory, and approximate Bayesian inference within a single cortical microcircuit, offering fresh insights into the brain's canonical computation and guiding the design of biologically plausible artificial neural architectures.

皮层环路工作记忆贝叶斯推断神经建模

Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。