用多视角对比学习提升脑电图帕金森病跨数据集检测能力

Electroencephalography has been validated as an effective technique for detecting Parkinson's disease,particularly in its early stages.However,the high cost of EEG data annotation often results in limited dataset size and considerable discrepancies across datasets,including differences in acquisition protocols and subject demographics,significantly hinder the robustness and generalizability of models in cross-dataset detection scenarios.To address such challenges,this paper proposes a semi-supervised learning framework named MCLPD,which integrates multi-view contrastive pre-training with lightweight supervised fine-tuning to enhance cross-dataset PD detection performance.During pre-training,MCLPD uses self-supervised learning on the unlabeled UNM dataset.To build contrastive pairs,it applies dual augmentations in both time and frequency domains,which enrich the data and naturally fuse time-frequency information.In the fine-tuning phase,only a small proportion of labeled data from another two datasets (UI and UC)is used for supervised optimization.Experimental results show that MCLPD achieves F1 scores of 0.91 on UI and 0.81 on UC using only 1%of labeled data,which further improve to 0.97 and 0.87,respectively,when 5%of labeled data is used.Compared to existing methods,MCLPD substantially improves cross-dataset generalization while reducing the dependency on labeled data,demonstrating the effectiveness of the proposed framework.