arXiv:2508.15947eess.SPcs.CY2025-08被引 1

用心电图自动连续监测住院患者呼吸频率,提升早期预警能力。

Continuous Determination of Respiratory Rate in Hospitalized Patients using Machine Learning Applied to Electrocardiogram Telemetry

  • 通过神经网络从心电图波形中提取呼吸变化信号,实现呼吸率自动估算。
  • 在多个验证集上平均绝对误差低于1.78次/分钟,表现稳定可靠。
  • 适合需要持续生命体征监测的普通病房患者,助力医院级早期预警系统。

呼吸频率(RR)是住院患者临床监测的重要生命体征,其变化与不良事件密切相关。人工手动计数呼吸频率存在不准确且耗时的问题。目前自动化监测仅用于部分重症患者,多数普通病房患者仍缺乏有效监测。本文训练神经网络(NN),从心电图(ECG)遥测波形中自动标注呼吸频率,因生物信号中包含多种呼吸相关变化特征。模型在多个验证集(内部、外部,不同标签来源)上表现优异,最差情况下平均绝对误差低于1.78次/分钟(bpm)。临床效用通过回顾性分析两组发生呼吸衰竭等不良事件的患者群体得以验证,发现连续呼吸频率监测可清晰反映与气管插管事件高度相关的动态变化。本研究展示了将现有遥测系统与人工智能结合,实现精准、自动、可扩展的患者监测,为构建基于AI的全院级早期预警系统(EWS)提供了范例。

原文摘要 · Abstract (English)

Respiration rate (RR) is an important vital sign for clinical monitoring of hospitalized patients, with changes in RR being strongly tied to changes in clinical status leading to adverse events. Human labels for RR, based on counting breaths, are known to be inaccurate and time consuming for medical staff. Automated monitoring of RR is in place for some patients, typically those in intensive care units (ICUs), but is absent for the majority of inpatients on standard medical wards who are still at risk for clinical deterioration. This work trains a neural network (NN) to label RR from electrocardiogram (ECG) telemetry waveforms, which like many biosignals, carry multiple signs of respiratory variation. The NN shows high accuracy on multiple validation sets (internal and external, same and different sources of RR labels), with mean absolute errors less than 1.78 breaths per minute (bpm) in the worst case. The clinical utility of such a technology is exemplified by performing a retrospective analysis of two patient cohorts that suffered adverse events including respiratory failure, showing that continuous RR monitoring could reveal dynamics that strongly tracked with intubation events. This work exemplifies the method of combining pre-existing telemetry monitoring systems and artificial intelligence (AI) to provide accurate, automated and scalable patient monitoring, all of which builds towards an AI-based hospital-wide early warning system (EWS).

呼吸监测心电图AI医疗早期预警

Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。