对比不同几何与输入维度,发现2D U-Net在稀疏采样伪影修正中表现最优。
Beam Geometry and Input Dimensionality: Impact on Sparse-Sampling Artifact Correction for Clinical CT with U-Nets
- 采用2D、2.5D、3D输入数据,分别训练U-Net模型以评估维度影响
- 在所有几何条件下,2D切片输入的模型在MSE和SSIM上均最佳
- 研究结果对临床CT伪影校正中输入设计具有指导意义
本研究旨在探究不同束几何及输入数据维度对临床CT稀疏采样条纹伪影校正任务中U-Net性能的影响,通过引入体素上下文提升去伪影效果。从慕尼黑工业大学附属医院(TUM Klinikum rechts der Isar)回顾性选取22例受试者(2016年1月至2018年12月)。使用Astra工具箱模拟平行、扇形及锥形束几何下的稀疏采样CT数据,全视图扫描设为2048视角。训练集包含14例,测试集为8例。针对维度研究,除512×512的2D CT图像外,还将扫描数据预处理为'2.5D'和3D形式:将每一体积分割为64×64×64体素块,3D数据指单个64体素块;每个块中心生成轴向、冠状、矢状三个64×64二维切片,重组为64×64×3图像作为2.5D数据。模型性能通过均方误差(MSE)和结构相似性指数(SSIM)评估。结果显示,在所有束几何下,基于轴向2D切片训练的2D U-Net在MSE和SSIM上均优于2.5D与3D输入数据。
原文摘要 · Abstract (English)
This study aims to investigate the effect of various beam geometries and dimensions of input data on the sparse-sampling streak artifact correction task with U-Nets for clinical CT scans as a means of incorporating the volumetric context into artifact reduction tasks to improve model performance. A total of 22 subjects were retrospectively selected (01.2016-12.2018) from the Technical University of Munich's research hospital, TUM Klinikum rechts der Isar. Sparsely-sampled CT volumes were simulated with the Astra toolbox for parallel, fan, and cone beam geometries. 2048 views were taken as full-view scans. 2D and 3D U-Nets were trained and validated on 14, and tested on 8 subjects, respectively. For the dimensionality study, in addition to the 512x512 2D CT images, the CT scans were further pre-processed to generate a so-called '2.5D', and 3D data: Each CT volume was divided into 64x64x64 voxel blocks. The 3D data refers to individual 64-voxel blocks. An axial, coronal, and sagittal cut through the center of each block resulted in three 64x64 2D patches that were rearranged as a single 64x64x3 image, proposed as 2.5D data. Model performance was assessed with the mean squared error (MSE) and structural similarity index measure (SSIM). For all geometries, the 2D U-Net trained on axial 2D slices results in the best MSE and SSIM values, outperforming the 2.5D and 3D input data dimensions.
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