arXiv:2508.18260cs.CL2025-08AAAI被引 8

MIRAGE通过并行图检索增强推理链,提升医疗问答准确性和可解释性。

MIRAGE: Scaling Test-Time Inference with Parallel Graph-Retrieval-Augmented Reasoning Chains

  • 将复杂问题分解为实体导向子问题,生成多条并行推理链
  • 在医学知识图谱中动态扩展邻居、多跳遍历获取证据,跨链验证答案
  • 相比GPT-4o等模型,医疗问答准确率更高,且推理过程可追溯

大型推理模型(LRMs)在测试时通过思维链提示实现显著进展。现有方法如search-o1将检索增强生成(RAG)融入多步推理,但依赖单一线性推理链,且以非结构化、上下文无关的方式处理文本信息,导致错误积累,限制了其在医疗问答任务中的有效性。为此,我们提出MIRAGE(多链推理与检索增强图探索),一种新型测试时可扩展的推理框架,在结构化医学知识图谱上执行动态多链推理。具体而言,MIRAGE:1)将复杂查询分解为基于实体的子问题;2)执行并行推理链;3)通过邻域扩展和多跳遍历自适应检索证据;4)利用跨链验证整合答案以解决矛盾。在三个医疗QA基准(GenMedGPT-5k、CMCQA、ExplainCPE)上的实验表明,MIRAGE在自动与人工评估中均持续优于GPT-4o、Tree-of-Thought变体及其他检索增强基线。此外,通过生成可追踪每条事实主张的显式推理链,显著提升可解释性,适用于复杂的医疗推理场景。代码将公开供进一步研究。

原文摘要 · Abstract (English)

Large reasoning models (LRMs) have shown significant progress in test-time scaling through chain-of-thought prompting. Current approaches like search-o1 integrate retrieval augmented generation (RAG) into multi-step reasoning processes but rely on a single, linear reasoning chain while incorporating unstructured textual information in a flat, context-agnostic manner. As a result, these approaches can lead to error accumulation throughout the reasoning chain, which significantly limits its effectiveness in medical question-answering (QA) tasks where both accuracy and traceability are critical requirements. To address these challenges, we propose MIRAGE (Multi-chain Inference with Retrieval-Augmented Graph Exploration), a novel test-time scalable reasoning framework that performs dynamic multi-chain inference over structured medical knowledge graphs. Specifically, MIRAGE 1) decomposes complex queries into entity-grounded sub-questions, 2) executes parallel inference chains, 3) retrieves evidence adaptively via neighbor expansion and multi-hop traversal, and 4) integrates answers using cross-chain verification to resolve contradictions. Experiments on three medical QA benchmarks (GenMedGPT-5k, CMCQA, and ExplainCPE) show that MIRAGE consistently outperforms GPT-4o, Tree-of-Thought variants, and other retrieval-augmented baselines in both automatic and human evaluations. Additionally, MIRAGE improves interpretability by generating explicit reasoning chains that trace each factual claim to concrete chains within the knowledge graph, making it well-suited for complex medical reasoning scenarios. The code will be available for further research.

医疗推理知识图谱多链推理RAG

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