arXiv:2508.19361cs.LGcs.AI2025-08被引 1

用短时心电数据提前两小时预测房颤,模型轻量高效。

Atrial Fibrillation Prediction Using a Lightweight Temporal Convolutional and Selective State Space Architecture

  • 结合时序卷积与选择性状态空间,用RR间期实现高效建模。
  • 提前两小时预测准确率超90%,参数仅7.35万,计算量极低。
  • 适合临床早期干预,尤其适用于可穿戴设备实时监测。

房颤是常见心律失常,可导致中风、心力衰竭等并发症。现有算法对持续性房颤检测效果良好,但对发作突然、持续时间短的阵发性房颤(PAF)往往漏检,而未被发现的PAF可能进展为持续性房颤,增加死亡风险。早期预测房颤可通过β受体阻滞剂等药物干预延缓进展。本研究提出一种轻量化深度学习模型,仅使用心电图中的RR间期(RRIs),融合时序卷积网络(TCN)与选择性状态空间模型Mamba,实现高效并行序列建模,以实现房颤早期预测。在个体化测试中,模型达到敏感度0.908、特异度0.933、F1分数0.930、AUROC 0.972、AUPRC 0.932。模型仅含73.5千参数和38.3 MFLOPs,优于传统CNN-RNN方法,在准确率与模型紧凑性上均更优。值得注意的是,该模型仅需30分钟输入数据即可提前两小时预测房颤,为预防性干预提供充足时间窗口。

原文摘要 · Abstract (English)

Atrial fibrillation (AF) is the most common arrhythmia, increasing the risk of stroke, heart failure, and other cardiovascular complications. While AF detection algorithms perform well in identifying persistent AF, early-stage progression, such as paroxysmal AF (PAF), often goes undetected due to its sudden onset and short duration. However, undetected PAF can progress into sustained AF, increasing the risk of mortality and severe complications. Early prediction of AF offers an opportunity to reduce disease progression through preventive therapies, such as catecholamine-sparing agents or beta-blockers. In this study, we propose a lightweight deep learning model using only RR Intervals (RRIs), combining a Temporal Convolutional Network (TCN) for positional encoding with Mamba, a selective state space model, to enable early prediction of AF through efficient parallel sequence modeling. In subject-wise testing results, our model achieved a sensitivity of 0.908, specificity of 0.933, F1-score of 0.930, AUROC of 0.972, and AUPRC of 0.932. Additionally, our method demonstrates high computational efficiency, with only 73.5 thousand parameters and 38.3 MFLOPs, outperforming traditional Convolutional Neural Network-Recurrent Neural Network (CNN-RNN) approaches in both accuracy and model compactness. Notably, the model can predict AF up to two hours in advance using just 30 minutes of input data, providing enough lead time for preventive interventions.

房颤预测轻量化模型时间序列医疗AI

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