arXiv:2508.21680cs.CV2025-08被引 1

用点击提示提升全身PET/CT病灶分割精度,让医生高效修正结果。

Towards Interactive Lesion Segmentation in Whole-Body PET/CT with Promptable Models

  • 将用户点击转为距离图输入,替代传统高斯核编码。
  • 在多中心数据上降低误报和漏报,交叉验证性能最优。
  • 适合需要人机协作的临床影像分析场景。

全身PET/CT是肿瘤影像的核心手段,但因示踪剂分布不均、生理摄取及多中心差异,病灶分割仍具挑战。尽管全自动方法已有进展,临床仍需保持人工参与以高效优化预测掩码。autoPET/CT IV挑战为此引入基于模拟用户提示的交互式分割任务。本文提交任务1方案,基于获奖的autoPET III nnU-Net框架,通过将用户提供的前景与背景点击编码为额外输入通道,扩展其交互能力。系统研究了空间提示表示方式,发现欧氏距离变换(EDT)编码始终优于高斯核。此外,提出在线模拟用户交互与定制点采样策略,增强真实提示条件下的鲁棒性。基于EDT的模型集成在有无外部数据训练下均表现最佳,显著减少假阳性与假阴性。结果表明,可提示模型能有效支持多示踪剂、多中心PET/CT中的高效人机协同分割流程。代码开源:https://github.com/MIC-DKFZ/autoPET-interactive

原文摘要 · Abstract (English)

Whole-body PET/CT is a cornerstone of oncological imaging, yet accurate lesion segmentation remains challenging due to tracer heterogeneity, physiological uptake, and multi-center variability. While fully automated methods have advanced substantially, clinical practice benefits from approaches that keep humans in the loop to efficiently refine predicted masks. The autoPET/CT IV challenge addresses this need by introducing interactive segmentation tasks based on simulated user prompts. In this work, we present our submission to Task 1. Building on the winning autoPET III nnU-Net pipeline, we extend the framework with promptable capabilities by encoding user-provided foreground and background clicks as additional input channels. We systematically investigate representations for spatial prompts and demonstrate that Euclidean Distance Transform (EDT) encodings consistently outperform Gaussian kernels. Furthermore, we propose online simulation of user interactions and a custom point sampling strategy to improve robustness under realistic prompting conditions. Our ensemble of EDT-based models, trained with and without external data, achieves the strongest cross-validation performance, reducing both false positives and false negatives compared to baseline models. These results highlight the potential of promptable models to enable efficient, user-guided segmentation workflows in multi-tracer, multi-center PET/CT. Code is publicly available at https://github.com/MIC-DKFZ/autoPET-interactive

医学图像交互分割PET/CT提示学习

Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。