arXiv:2508.21793cs.LGcs.AI2025-08中稿 · The 16th ACM Confe…被引 13

MoE-Health用专家混合模型自动适配缺失医疗数据,提升预测准确性。

MoE-Health: A Mixture of Experts Framework for Robust Multimodal Healthcare Prediction

  • 基于动态门控机制,按可用数据自动选择专家网络融合信息
  • 在MIMIC-IV上三项临床任务均优于现有方法,对缺模态鲁棒
  • 适合真实医院中数据不全、异构的复杂环境使用

医疗系统生成多种多模态数据,包括电子健康记录(EHR)、临床笔记和医学影像。有效利用这些数据进行临床预测具有挑战性,尤其在真实样本中常存在不同或不完整的模态。现有方法通常需要完整模态数据或依赖人工选择策略,限制了其在真实临床环境中应用,因患者与机构间数据可用性差异大。为此,我们提出MoE-Health,一种新型的专家混合(Mixture of Experts)框架,专为医疗预测中的鲁棒多模态融合设计。该架构通过专用专家网络与动态门控机制,根据可用模态动态选择并组合相关专家,灵活适应不同数据缺失场景。我们在MIMIC-IV数据集上评估了该框架在三项关键临床预测任务上的表现:院内死亡率预测、住院时长过长预测及再入院预测。实验结果表明,相较于现有多模态融合方法,MoE-Health在不同模态可用性模式下均表现出更优性能,有效整合多模态信息,显著提升预测效果与鲁棒性,特别适用于数据异构且不完整的多样化医疗环境部署。

原文摘要 · Abstract (English)

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples often present with varied or incomplete modalities. Existing approaches typically require complete modality data or rely on manual selection strategies, limiting their applicability in real-world clinical settings where data availability varies across patients and institutions. To address these limitations, we propose MoE-Health, a novel Mixture of Experts framework designed for robust multimodal fusion in healthcare prediction. MoE-Health architecture is specifically developed to handle samples with differing modalities and improve performance on critical clinical tasks. By leveraging specialized expert networks and a dynamic gating mechanism, our approach dynamically selects and combines relevant experts based on available data modalities, enabling flexible adaptation to varying data availability scenarios. We evaluate MoE-Health on the MIMIC-IV dataset across three critical clinical prediction tasks: in-hospital mortality prediction, long length of stay, and hospital readmission prediction. Experimental results demonstrate that MoE-Health achieves superior performance compared to existing multimodal fusion methods while maintaining robustness across different modality availability patterns. The framework effectively integrates multimodal information, offering improved predictive performance and robustness in handling heterogeneous and incomplete healthcare data, making it particularly suitable for deployment in diverse healthcare environments with heterogeneous data availability.

多模态融合医疗预测专家混合缺模态

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