arXiv:2509.02923cs.LG2025-09综述被引 1

提出糖尿病足溃疡足部减压鞋处方的临床决策支持框架

A Narrative Review of Clinical Decision Support Systems in Offloading Footwear for Diabetes-Related Foot Ulcers

  • 整合规则、优化与可解释机器学习构建混合决策系统
  • 需满足200 kPa压力阈值或减少25%-30%才能有效预防溃疡
  • 适合关注临床落地、可解释性与长期疗效评估的研究者

为改善糖尿病足溃疡(DFUs)患者足部减压鞋的处方质量,本文对45项研究(含12项指南/规范、25个基于知识的系统、8个机器学习应用)进行了主题综述。现有方法存在特征选择不统一、个性化不足及评估方式碎片化等问题。指南多依赖≤200 kPa压力阈值或≥25–30%压力降幅,但缺乏可操作的特征输出;知识系统采用规则与传感器驱动逻辑,融合压力监测、依从性追踪与可用性测试;机器学习研究虽具高精度预测与生成能力,但可解释性差且临床验证不足。评估方面,各类型研究侧重不同:规范偏重生物力学测试,知识系统关注使用体验与依从性,机器学习则聚焦技术指标,与长期结局关联弱。为此,本文提出五部分临床决策支持系统(CDSS)框架:(1)最小可行数据集;(2)规则、优化与可解释机器学习混合架构;(3)结构化特征级输出;(4)持续验证与评估机制;(5)与临床及远程医疗流程集成。该框架旨在推动可扩展、以患者为中心的糖尿病足护理系统发展,强调数据互操作性、模型可解释性与结果导向评估。

原文摘要 · Abstract (English)

Offloading footwear helps prevent and treat diabetic foot ulcers (DFUs) by lowering plantar pressure (PP), yet prescription decisions remain fragmented: feature selection varies, personalization is limited, and evaluation practices differ. We performed a narrative review of 45 studies (12 guidelines/protocols, 25 knowledge-based systems, 8 machine-learning applications) published to Aug 2025. We thematically analyzed knowledge type, decision logic, evaluation methods, and enabling technologies. Guidelines emphasize PP thresholds (<=200 kPa or >=25--30\% reduction) but rarely yield actionable, feature-level outputs. Knowledge-based systems use rule- and sensor-driven logic, integrating PP monitoring, adherence tracking, and usability testing. ML work introduces predictive, optimization, and generative models with high computational accuracy but limited explainability and clinical validation. Evaluation remains fragmented: protocols prioritize biomechanical tests; knowledge-based systems assess usability/adherence; ML studies focus on technical accuracy with weak linkage to long-term outcomes. From this synthesis we propose a five-part CDSS framework: (1) a minimum viable dataset; (2) a hybrid architecture combining rules, optimization, and explainable ML; (3) structured feature-level outputs; (4) continuous validation and evaluation; and (5) integration with clinical and telehealth workflows. This framework aims to enable scalable, patient-centered CDSSs for DFU care; prioritizing interoperable datasets, explainable models, and outcome-focused evaluation will be key to clinical adoption.

临床决策糖尿病足减压鞋可解释AI

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