arXiv:2509.04951cs.LG2025-09被引 1

用深度学习从脑电图中精准识别眨眼,助力认知与帕金森病研究。

Detecting Blinks in Healthy and Parkinson's EEG: A Deep Learning Perspective

  • 采用混合CNN-RNN模型,直接处理原始脑电信号进行眨眼分割。
  • 在健康人群上最高准确率达95.8%,帕金森患者也达75.8%。
  • 无需复杂预处理,适合临床脑电分析与神经疾病监测。

脑电图中的眨眼常被视为干扰伪迹,但近年研究表明眨眼频率及其变异性是评估认知负荷、注意力及潜在神经疾病的生理标志。本文通过评估多种深度学习模型,实现对脑电信号中不自主眨眼与非眨眼段的精准分割。提出使用1、3或5个额叶电极的检测流程,将任务建模为序列到序列问题,在包括标准循环网络、卷积神经网络(标准与深度可分离)、时序卷积网络(TCN)、基于Transformer的模型及混合架构等多种网络结构上进行测试。所有模型均在原始脑电信号上训练,无复杂预处理。实验基于加州大学圣地亚哥分校(UCSD)公开数据集,包含15名健康受试者和16名帕金森病患者,验证了模型对震颤的鲁棒性。其中,CNN-RNN混合模型表现最优,在健康组中分别达到93.8%、95.4%和95.8%的准确率,在帕金森患者组中分别为73.8%、75.4%和75.8%。研究比较了不同神经网络在脑电眨眼分割任务中的性能,支持眨眼率等统计指标的计算。

原文摘要 · Abstract (English)

Blinks in electroencephalography (EEG) are often treated as unwanted artifacts. However, recent studies have demonstrated that blink rate and its variability are important physiological markers to monitor cognitive load, attention, and potential neurological disorders. This paper addresses the critical task of accurate blink detection by evaluating various deep learning models for segmenting EEG signals into involuntary blinks and non-blinks. We present a pipeline for blink detection using 1, 3, or 5 frontal EEG electrodes. The problem is formulated as a sequence-to-sequence task and tested on various deep learning architectures including standard recurrent neural networks, convolutional neural networks (both standard and depth-wise), temporal convolutional networks (TCN), transformer-based models, and hybrid architectures. The models were trained on raw EEG signals with minimal pre-processing. Training and testing was carried out on a public dataset of 31 subjects collected at UCSD. This dataset consisted of 15 healthy participants and 16 patients with Parkinson's disease allowing us to verify the model's robustness to tremor. Out of all models, CNN-RNN hybrid model consistently outperformed other models and achieved the best blink detection accuracy of 93.8%, 95.4% and 95.8% with 1, 3, and 5 channels in the healthy cohort and correspondingly 73.8%, 75.4% and 75.8% in patients with PD. The paper compares neural networks for the task of segmenting EEG recordings to involuntary blinks and no blinks allowing for computing blink rate and other statistics.

脑电图眨眼检测帕金森深度学习

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