提升心脏超声序列仿真真实度,精准模拟斑点变化。
Generation of realistic cardiac ultrasound sequences with ground truth motion and speckle decorrelation
- 基于真实数据构建时变斑点相干图,动态建模散射特性。
- 在98例患者数据上验证,仿真序列与真实序列相关性更接近。
- 适合需要高保真超声数据的医学影像算法训练者。
仿真超声图像序列对于左心室应变估计的机器学习算法训练与验证至关重要。现有仿真流程虽能生成对应运动真值的序列,但因未考虑斑点去相关现象,导致真实性不足。本文提出一种改进的仿真框架,显式建模斑点去相关特性。方法基于真实超声序列和心肌分割,生成引导图像形成的网格;不再使用固定的心肌与背景散射体比例,而是引入随时间动态变化的相干图,该图由真实超声数据中直接测量的相关系数得出,确保仿真序列能捕捉临床中观察到的时序变化特征。在CAMUS数据库98例患者数据上评估了仿真结果的逼真度,通过对比真实与仿真图像的相关曲线进行分析。所提方法相比基线管道平均绝对误差更低,表明其更准确地再现了临床数据中的去相关行为。
原文摘要 · Abstract (English)
Simulated ultrasound image sequences are key for training and validating machine learning algorithms for left ventricular strain estimation. Several simulation pipelines have been proposed to generate sequences with corresponding ground truth motion, but they suffer from limited realism as they do not consider speckle decorrelation. In this work, we address this limitation by proposing an improved simulation framework that explicitly accounts for speckle decorrelation. Our method builds on an existing ultrasound simulation pipeline by incorporating a dynamic model of speckle variation. Starting from real ultrasound sequences and myocardial segmentations, we generate meshes that guide image formation. Instead of applying a fixed ratio of myocardial and background scatterers, we introduce a coherence map that adapts locally over time. This map is derived from correlation values measured directly from the real ultrasound data, ensuring that simulated sequences capture the characteristic temporal changes observed in practice. We evaluated the realism of our approach using ultrasound data from 98 patients in the CAMUS database. Performance was assessed by comparing correlation curves from real and simulated images. The proposed method achieved lower mean absolute error compared to the baseline pipeline, indicating that it more faithfully reproduces the decorrelation behavior seen in clinical data.
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