arXiv:2509.08007eess.IVcs.AI2025-09中稿 · publication in the…被引 14

用专家标注区域指导模型,让少样本医学图像诊断更准且可解释。

Expert-Guided Explainable Few-Shot Learning for Medical Image Diagnosis

  • 用放射科医生提供的病灶区域引导模型注意力,提升学习效率。
  • 在脑瘤和胸片数据集上准确率分别提升至83.61%和73.29%。
  • 适合医疗AI研发者与临床医生,增强诊断可信度。

医学图像分析常因专家标注数据有限而面临挑战,影响模型泛化能力与临床应用。本文提出一种专家引导的可解释少样本学习框架,将放射科医生提供的感兴趣区域(ROIs)融入训练过程,同时提升分类性能与可解释性。利用Grad-CAM进行空间注意力监督,设计基于Dice相似度的解释损失,使模型注意力在训练中对齐诊断相关区域。该损失与原型网络目标联合优化,促使模型在数据稀缺条件下聚焦临床有意义特征。在BraTS(MRI)和VinDr-CXR(胸部X光)两个数据集上评估,相比非引导模型,准确率分别从77.09%提升至83.61%,从54.33%提升至73.29%。Grad-CAM可视化进一步验证了专家引导训练能持续对齐注意力至诊断区域,提升预测可靠性与临床可信度。结果表明,引入专家引导的注意力监督可有效弥合少样本医学图像诊断中性能与可解释性的差距。

原文摘要 · Abstract (English)

Medical image analysis often faces significant challenges due to limited expert-annotated data, hindering both model generalization and clinical adoption. We propose an expert-guided explainable few-shot learning framework that integrates radiologist-provided regions of interest (ROIs) into model training to simultaneously enhance classification performance and interpretability. Leveraging Grad-CAM for spatial attention supervision, we introduce an explanation loss based on Dice similarity to align model attention with diagnostically relevant regions during training. This explanation loss is jointly optimized with a standard prototypical network objective, encouraging the model to focus on clinically meaningful features even under limited data conditions. We evaluate our framework on two distinct datasets: BraTS (MRI) and VinDr-CXR (Chest X-ray), achieving significant accuracy improvements from 77.09% to 83.61% on BraTS and from 54.33% to 73.29% on VinDr-CXR compared to non-guided models. Grad-CAM visualizations further confirm that expert-guided training consistently aligns attention with diagnostic regions, improving both predictive reliability and clinical trustworthiness. Our findings demonstrate the effectiveness of incorporating expert-guided attention supervision to bridge the gap between performance and interpretability in few-shot medical image diagnosis.

少样本学习医学图像可解释性注意力引导

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