用手机拍皮肤照,AI能准确识别砷中毒早期症状。
An End-to-End Deep Learning Framework for Arsenicosis Diagnosis Using Mobile-Captured Skin Images
- 端到端深度学习框架,用手机图像自动诊断砷中毒。
- 基于Transformer的模型准确率达86%,优于传统CNN。
- 可视化技术提升可解释性,适合基层医疗使用。
砷中毒是南亚和东南亚严重的公共卫生问题,主要由长期饮用含砷水引起。早期皮肤表现具有临床意义但常被漏诊,尤其在缺乏皮肤科医生的农村地区。本研究提出一种基于手机拍摄皮肤图像的端到端深度学习诊断框架。构建了包含20类、超过11000张图像的数据集,涵盖砷中毒及其他皮肤病。对比了多种深度学习模型,包括卷积神经网络(CNN)和基于Transformer的模型。结果显示,Transformer模型显著优于CNN,其中Swin Transformer达到最高准确率86%。通过LIME和Grad-CAM实现模型可解释性,验证模型关注病变区域,增强临床可信度,并支持错误分析。外部验证样本也表现良好,证明模型具备泛化能力。该框架展示了深度学习在非侵入式、可及且可解释的砷中毒诊断中的潜力,可作为资源匮乏地区的实用筛查工具,促进早期发现与及时干预。
原文摘要 · Abstract (English)
Background: Arsenicosis is a serious public health concern in South and Southeast Asia, primarily caused by long-term consumption of arsenic-contaminated water. Its early cutaneous manifestations are clinically significant but often underdiagnosed, particularly in rural areas with limited access to dermatologists. Automated, image-based diagnostic solutions can support early detection and timely interventions. Methods: In this study, we propose an end-to-end framework for arsenicosis diagnosis using mobile phone-captured skin images. A dataset comprising 20 classes and over 11000 images of arsenic-induced and other dermatological conditions was curated. Multiple deep learning architectures, including convolutional neural networks (CNNs) and Transformer-based models, were benchmarked for arsenicosis detection. Model interpretability was integrated via LIME and Grad-CAM, while deployment feasibility was demonstrated through a web-based diagnostic tool. Results: Transformer-based models significantly outperformed CNNs, with the Swin Transformer achieving the best results (86\\% accuracy). LIME and Grad-CAM visualizations confirmed that the models attended to lesion-relevant regions, increasing clinical transparency and aiding in error analysis. The framework also demonstrated strong performance on external validation samples, confirming its ability to generalize beyond the curated dataset. Conclusion: The proposed framework demonstrates the potential of deep learning for non-invasive, accessible, and explainable diagnosis of arsenicosis from mobile-acquired images. By enabling reliable image-based screening, it can serve as a practical diagnostic aid in rural and resource-limited communities, where access to dermatologists is scarce, thereby supporting early detection and timely intervention.
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