arXiv:2509.12625cs.AI2025-09被引 1

将心电图转化为通用语言,让任意大模型都能分析且可解释。

ECG-aBcDe: Overcoming Model Dependence, Encoding ECG into a Universal Language for Any LLM

  • 构建心电图与自然语言的混合数据集,实现无需修改架构的直接微调。
  • 在跨数据集评估中BLEU-4达30.76,提升3.9倍,优于现有方法。
  • 支持双向转换与注意力热图生成,显著提升结果可解释性。

大语言模型(LLM)在心电图(ECG)分析中潜力巨大,但存在可迁移性差、时间尺度信息学习不足和可解释性弱等问题。当前方法依赖特定模型的心电图编码器,难以在不同LLM间迁移;同时由于Transformer结构限制,难以捕捉心电图固有的时间尺度信息,且其黑箱特性阻碍临床应用。为此,我们提出ECG-aBcDe,一种新型心电图编码方法,将心电图信号转化为任意大模型均可理解的通用语言。通过构建心电图语言与自然语言的混合数据集,实现预训练大模型的直接微调,具备“构建一次,处处可用”的能力。此外,该方法支持心电图与语言间的双向转换,可从心电图信号中提取注意力热图,极大增强可解释性。最后,显式编码时间尺度信息,缓解Transformer的局限性。实验表明,相比现有方法,本方法在ROUGE-L和METEOR上表现相当,尤其在BLEU-4指标上显著提升:在同数据集评估中提升2.8倍,在跨数据集评估中提升3.9倍,分别达到42.58和30.76,充分验证了新范式的可行性。

原文摘要 · Abstract (English)

Large Language Models (LLMs) hold significant promise for electrocardiogram (ECG) analysis, yet challenges remain regarding transferability, time-scale information learning, and interpretability. Current methods suffer from model-specific ECG encoders, hindering transfer across LLMs. Furthermore, LLMs struggle to capture crucial time-scale information inherent in ECGs due to Transformer limitations. And their black-box nature limits clinical adoption. To address these limitations, we introduce ECG-aBcDe, a novel ECG encoding method that transforms ECG signals into a universal ECG language readily interpretable by any LLM. By constructing a hybrid dataset of ECG language and natural language, ECG-aBcDe enables direct fine-tuning of pre-trained LLMs without architectural modifications, achieving "construct once, use anywhere" capability. Moreover, the bidirectional convertibility between ECG and ECG language of ECG-aBcDe allows for extracting attention heatmaps from ECG signals, significantly enhancing interpretability. Finally, ECG-aBcDe explicitly represents time-scale information, mitigating Transformer limitations. This work presents a new paradigm for integrating ECG analysis with LLMs. Compared with existing methods, our method achieves competitive performance on ROUGE-L and METEOR. Notably, it delivers significant improvements in the BLEU-4, with improvements of 2.8 times and 3.9 times in in-dataset and cross-dataset evaluations, respectively, reaching scores of 42.58 and 30.76. These results provide strong evidence for the feasibility of the new paradigm.

心电图分析大模型可解释性通用编码

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