毫米级软体机器人可磁控重编程,实现五种手术功能。
Miniature soft robot with magnetically reprogrammable surgical functions
- 通过可重编程磁化分布实现多任务执行
- 支持六自由度运动,可在复杂环境移动
- 弱磁场下可控,适合深部体内操作
微型机器人作为无缆驱动器,在微创手术中具有显著潜力,可提升安全性并实现前所未有的治疗。磁驱动微型机器人最具功能性和灵活性,但现有系统受限于最多两种内置功能或仅五自由度运动,且需强磁场近距离(<4 cm)操控。本文提出一种毫米级软体机器人,其磁化分布可远程重编程,实现五种手术功能:药物释放、切割凝胶模拟组织、抓取、样本存储及远端加热。该机器人具备完整六自由度运动能力,包括沿净磁矩的第六自由度旋转,可实现滚动和双锚爬行,穿越传统五自由度机器人无法通行的非结构化环境。所用磁场均值不超过65 mT,梯度为1.5 T/m,理论上可无害穿透生物组织,确保人体深处仍可控制。本工作标志着软驱动器的重大进展,有望推动具空前功能的无缆微型机器人在微创治疗中的革命性应用。
原文摘要 · Abstract (English)
Miniature robots are untethered actuators, which have significant potential to make existing minimally invasive surgery considerably safer and painless, and enable unprecedented treatments because they are much smaller and dexterous than existing surgical robots. Of the miniature robots, the magnetically actuated ones are the most functional and dexterous. However, existing magnetic miniature robots are currently impractical for surgery because they are either restricted to possessing at most two on-board functionalities or having limited five degrees-of-freedom (DOF) locomotion. Some of these actuators are also only operational under specialized environments where actuation from strong external magnets must be at very close proximity (< 4 cm away). Here we present a millimeter-scale soft robot where its magnetization profile can be reprogrammed upon command to perform five surgical functionalities: drug-dispensing, cutting through biological tissues (simulated with gelatin), gripping, storing (biological) samples and remote heating. By possessing full six-DOF motions, including the sixth-DOF rotation about its net magnetic moment, our soft robot can also roll and two-anchor crawl across challenging unstructured environments, which are impassable by its five-DOF counterparts. Because our actuating magnetic fields are relatively uniform and weak (at most 65 mT and 1.5 T/m), such fields can theoretically penetrate through biological tissues harmlessly and allow our soft robot to remain controllable within the depths of the human body. We envision that this work marks a major milestone for the advancement of soft actuators, and towards revolutionizing minimally invasive treatments with untethered miniature robots that have unprecedented functionalities.
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