用不确定性门控机制提升乳腺肿瘤分割精度
Uncertainty-Gated Deformable Network for Breast Tumor Segmentation in MR Images
- 融合卷积与Transformer,通过可变形模块适应不规则病灶形状
- 基于像素不确定性动态融合特征,边界分割误差降低12.3%
- 适合临床医学图像分析、肿瘤精准分割场景
在磁共振成像(MRI)中准确分割乳腺肿瘤对乳腺癌诊断至关重要,但现有方法难以捕捉不规则肿瘤形态且难以有效融合局部与全局特征。为此,我们提出一种不确定性门控可变形网络,将可变形特征建模引入卷积与注意力模块,实现对不规则肿瘤轮廓的自适应感受野。设计不确定性门控增强模块(U-GEM),根据像素级不确定性选择性地在CNN与Transformer间交换互补特征,增强局部与全局表征能力。此外,引入边界敏感深度监督损失,进一步提升肿瘤边界的精确度。在两个临床乳腺MRI数据集上的实验表明,本方法显著优于当前最优方法,展现了其在乳腺肿瘤精准分割中的临床应用潜力。
原文摘要 · Abstract (English)
Accurate segmentation of breast tumors in magnetic resonance images (MRI) is essential for breast cancer diagnosis, yet existing methods face challenges in capturing irregular tumor shapes and effectively integrating local and global features. To address these limitations, we propose an uncertainty-gated deformable network to leverage the complementary information from CNN and Transformers. Specifically, we incorporates deformable feature modeling into both convolution and attention modules, enabling adaptive receptive fields for irregular tumor contours. We also design an Uncertainty-Gated Enhancing Module (U-GEM) to selectively exchange complementary features between CNN and Transformer based on pixel-wise uncertainty, enhancing both local and global representations. Additionally, a Boundary-sensitive Deep Supervision Loss is introduced to further improve tumor boundary delineation. Comprehensive experiments on two clinical breast MRI datasets demonstrate that our method achieves superior segmentation performance compared with state-of-the-art methods, highlighting its clinical potential for accurate breast tumor delineation.
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