用热核方法提升医疗多视角聚类的隐私保护与准确性
FedHK-MVFC: Federated Heat Kernel Multi-View Clustering
- 通过热核距离转换,融合几何结构信息增强多视图相似性度量
- 在10,000条合成患者数据上实现更高聚类准确率和更低通信开销
- 适合需跨医院协作且遵守HIPAA的医疗数据隐私分析场景
在分布式人工智能与隐私导向的医疗应用背景下,本文提出一种将量子场论与联邦医疗分析结合的多视图聚类框架。该方法利用谱分析中的热核系数,将欧氏距离转化为反映数据结构的几何感知相似性度量。通过热核距离(HKD)变换实现收敛性保障。开发了两种算法:用于中心化分析的热核增强多视图模糊聚类(HK-MVFC),以及用于跨医院安全隐私学习的联邦热核多视图模糊聚类(FedHK-MVFC)。后者采用差分隐私与安全聚合,满足HIPAA合规要求。在两所医院共10,000条合成心血管患者数据上的测试表明,相比集中式方法,该方法提升了聚类准确率、减少了通信开销并保持高效性。验证结果支持其在心电图(ECG)、心脏影像及行为数据联合表型分析中的实用性。理论贡献包括可证明收敛的更新规则、自适应视图加权机制与隐私保护协议,为医疗领域几何感知联邦学习树立新标准。
原文摘要 · Abstract (English)
In the realm of distributed artificial intelligence (AI) and privacy-focused medical applications, this paper proposes a multi-view clustering framework that links quantum field theory with federated healthcare analytics. The method uses heat kernel coefficients from spectral analysis to convert Euclidean distances into geometry-aware similarity measures that capture the structure of diverse medical data. The framework is presented through the heat kernel distance (HKD) transformation, which has convergence guarantees. Two algorithms have been developed: The first, Heat Kernel-Enhanced Multi-View Fuzzy Clustering (HK-MVFC), is used for central analysis. The second, Federated Heat Kernel Multi-View Fuzzy Clustering (FedHK-MVFC), is used for secure, privacy-preserving learning across hospitals. FedHK-MVFC uses differential privacy and secure aggregation to enable HIPAA-compliant collaboration. Tests on synthetic cardiovascular patient datasets demonstrate increased clustering accuracy, reduced communication, and retained efficiency compared to centralized methods. After being validated on 10,000 synthetic patient records across two hospitals, the methods proved useful for collaborative phenotyping involving electrocardiogram (ECG) data, cardiac imaging data, and behavioral data. The proposed methods' theoretical contributions include update rules with proven convergence, adaptive view weighting, and privacy-preserving protocols. These contributions establish a new standard for geometry-aware federated learning in healthcare, translating advanced mathematics into practical solutions for analyzing sensitive medical data while ensuring rigor and clinical relevance.
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