通过软约束正则化因果推断中的外推,提升模型泛化能力
Regularizing Extrapolation in Causal Inference
- 用可调节的软约束替代硬性非负权重限制,控制外推程度
- 在高维且弱正性条件下,显著降低因特征不平衡导致的误差
- 适用于需评估模型假设敏感性的实证研究,如临床试验外推
许多机器学习和因果推断中的估计器是线性平滑器,其预测为训练结果的加权平均。一些估计器(如普通最小二乘、核岭回归)允许权重任意为负,虽能缓解特征不平衡,但会增加对参数模型假设的依赖并提高方差;而重要性加权和随机森林等则隐式限制权重非负,降低对参数假设的依赖和方差,但平衡性更差。本文提出一个统一框架,直接惩罚外推程度,以软约束取代硬性非负约束,并引入超参数。我们推导了最坏情况下的外推误差界,揭示了一种新的“偏倚-偏倚-方差”权衡,包含特征不平衡、模型误设和估计方差带来的偏差,该权衡在高维及弱正性条件下尤为显著。进一步提出优化方法,在最小化不平衡的同时正则化该误差界,并可用于评估对参数假设的敏感性。通过合成实验与真实世界应用(将随机对照试验结果推广至目标人群)验证了该方法的有效性。
原文摘要 · Abstract (English)
Many common estimators in machine learning and causal inference are linear smoothers, where the prediction is a weighted average of the training outcomes. Some estimators, such as ordinary least squares and kernel ridge regression, allow for arbitrarily negative weights, which improve feature imbalance but often at the cost of increased dependence on parametric modeling assumptions and higher variance. By contrast, estimators like importance weighting and random forests (sometimes implicitly) restrict weights to be non-negative, reducing dependence on parametric modeling and variance at the cost of worse imbalance. In this paper, we propose a unified framework that directly penalizes the level of extrapolation, replacing the current practice of a hard non-negativity constraint with a soft constraint and corresponding hyperparameter. We derive a worst-case extrapolation error bound and introduce a novel "bias-bias-variance" tradeoff, encompassing biases due to feature imbalance, model misspecification, and estimator variance; this tradeoff is especially pronounced in high dimensions, particularly when positivity is poor. We then develop an optimization procedure that regularizes this bound while minimizing imbalance and outline how to use this approach as a sensitivity analysis for dependence on parametric modeling assumptions. We demonstrate the effectiveness of our approach through synthetic experiments and a real-world application, involving the generalization of randomized controlled trial estimates to a target population of interest.
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