arXiv:2509.19671cs.LG2025-09被引 1

用临床先验信息重新评估胸部X光模型,发现高风险患者上模型表现更差。

Revisiting Performance Claims for Chest X-Ray Models Using Clinical Context

  • 用出院摘要推断检查前患病概率,模拟医生判读时的上下文知识
  • 模型在高先验概率患者中表现显著下降,AUROC等指标明显降低
  • 模型性能高度依赖临床上下文分布,不适合直接推广到高危人群

公开的胸部X光(CXR)数据集长期作为医疗视觉模型的基准。然而,这些模型在平均情况下的优异表现未必反映其在真实多变临床环境中的实际价值,可能掩盖了在重要医学场景下的薄弱表现。本文引入临床上下文,对CXR诊断模型进行更全面评估。具体地,利用每张X光片之前的出院摘要,推导出各标签的“检查前概率”,作为医生判读时已有知识的代理。基于此,从两个维度分析模型性能:第一,分层分析显示,模型在高检查前概率人群中表现更差(以AUROC等指标衡量);第二,通过匹配和重加权控制先验概率后,发现当先验与当前影像标签相关性被打破时,模型性能显著下降,表明模型对临床上下文分布极为敏感。尤其在高先验概率病例中,视觉分类任务本质更难,揭示了模型在高风险人群中的临床实用性不足。

原文摘要 · Abstract (English)

Public datasets of Chest X-Rays (CXRs) have long been a popular benchmark for developing machine learning (ML) computer vision models in healthcare. However, the reported strong average-case performance of these models do not necessarily reflect their actual utility when used in heterogeneous clinical settings, potentially masking weaker performance in medically significant scenarios. In this work we use clinical context to provide a more holistic evaluation of models for CXR diagnosis. In particular, we use discharge summaries, recorded prior to each CXR, to derive a ``pre-CXR'' probability of each CXR label, as a proxy for existing contextual knowledge available to clinicians when interpreting CXRs. We use this measure to probe model performance along two dimensions: First, using a stratified analysis, we show that models tend to have lower performance (as measured by AUROC and other metrics) among individuals with higher pre-CXR probability. Second, by controlling for pre-CXR probability via matching and re-weighting, we demonstrate that performance degrades when the correlation is broken between prior context and the current CXR label, suggesting that model performance is highly sensitive to the underlying distribution of clinical context. Specifically, cases with high pre-test probabilities present a fundamentally more difficult visual classification task, highlighting a gap in clinical utility when models are applied to high-risk cohorts.

医学影像临床上下文模型评估胸部X光

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