arXiv:2509.20279cs.CVq-bio.QM2025-09被引 19

TissueLab让医学影像分析AI能实时互动、自我进化,提升诊断准确性。

A co-evolving agentic AI system for medical imaging analysis

  • 构建可协同进化的AI系统,自动规划并执行可解释的分析流程。
  • 在多种临床任务中表现超越现有视觉语言模型和同类系统。
  • 支持医生实时反馈,快速适应新疾病场景,适合医疗研究与临床转化。

代理型AI在医疗和生物医学研究中快速发展,但在医学影像分析领域,其性能与应用受限于缺乏稳健生态、工具集不足以及实时专家反馈缺失。本文提出「TissueLab」——一个协同进化的代理型AI系统,使研究人员能够直接提问,自动规划并生成可解释的工作流,并实现实时分析,专家可可视化中间结果并进行优化。TissueLab整合了病理学、放射学与空间组学领域的工具工厂,通过标准化各类工具的输入、输出与能力,智能决定何时及如何调用它们以解决科研与临床问题。在涵盖分期、预后与治疗规划等具有临床意义的量化任务中,TissueLab的表现优于端到端视觉语言模型(VLMs)及其他代理型AI系统(如GPT-5)。此外,TissueLab通过主动学习持续从临床医生处获取反馈,不断优化分类器与决策策略,在无需大规模数据或长期再训练的情况下,数分钟内即可实现对未见疾病情境的精准推理。作为可持续的开源生态系统发布,TissueLab旨在加速医学影像的计算研究与转化应用,并为下一代医学AI奠定基础。

原文摘要 · Abstract (English)

Agentic AI is rapidly advancing in healthcare and biomedical research. However, in medical image analysis, their performance and adoption remain limited due to the lack of a robust ecosystem, insufficient toolsets, and the absence of real-time interactive expert feedback. Here we present "TissueLab", a co-evolving agentic AI system that allows researchers to ask direct questions, automatically plan and generate explainable workflows, and conduct real-time analyses where experts can visualize intermediate results and refine them. TissueLab integrates tool factories across pathology, radiology, and spatial omics domains. By standardizing inputs, outputs, and capabilities of diverse tools, the system determines when and how to invoke them to address research and clinical questions. Across diverse tasks with clinically meaningful quantifications that inform staging, prognosis, and treatment planning, TissueLab achieves state-of-the-art performance compared with end-to-end vision-language models (VLMs) and other agentic AI systems such as GPT-5. Moreover, TissueLab continuously learns from clinicians, evolving toward improved classifiers and more effective decision strategies. With active learning, it delivers accurate results in unseen disease contexts within minutes, without requiring massive datasets or prolonged retraining. Released as a sustainable open-source ecosystem, TissueLab aims to accelerate computational research and translational adoption in medical imaging while establishing a foundation for the next generation of medical AI.

医学影像代理AI主动学习可解释性

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