arXiv:2509.24898cs.CV2025-09被引 3

用SVD和深度学习精准测算脊柱侧弯角度,提升诊断准确性。

Accurate Cobb Angle Estimation via SVD-Based Curve Detection and Vertebral Wedging Quantification

  • 基于SVD分析椎体形态,无需预设曲线模式,灵活检测多种侧弯类型。
  • 诊断准确率达83.45%,平均误差仅2.55°,在非典型病例中表现优异。
  • 提出椎体楔变指数(VWI),可预测病情进展,优于传统柯布角。

青少年特发性脊柱侧弯(AIS)全球患病率约为男童2.2%、女童4.8%。柯布角是评估病情严重程度的金标准,但人工测量存在显著观察者差异,影响诊断准确性。现有自动化方法多采用简化脊柱模型与预设曲线模式,难以应对临床复杂性。本文提出一种新型深度学习框架,可同时预测每节椎体的上、下终板角度及其对应中点坐标,真实保留进行性AIS中椎体楔变的解剖特征。模型结合HRNet主干与Swin-Transformer模块,并引入生物力学约束以增强特征提取。通过奇异值分解(SVD)直接分析椎体形态预测结果,实现无需预设曲线假设的灵活模式检测。基于630张10-18岁患者全脊柱正位片(经双阅片员严格标注),本方法达到83.45%诊断准确率和2.55°平均绝对误差。框架在分布外样本上表现出优异泛化能力。此外,提出椎体楔变指数(VWI),纵向分析显示其与侧弯进展具有显著预测关联,而传统柯布角无此关联,为早期筛查、个性化治疗和进展监测提供有力支持。

原文摘要 · Abstract (English)

Adolescent idiopathic scoliosis (AIS) is a common spinal deformity affecting approximately 2.2% of boys and 4.8% of girls worldwide. The Cobb angle serves as the gold standard for AIS severity assessment, yet traditional manual measurements suffer from significant observer variability, compromising diagnostic accuracy. Despite prior automation attempts, existing methods use simplified spinal models and predetermined curve patterns that fail to address clinical complexity. We present a novel deep learning framework for AIS assessment that simultaneously predicts both superior and inferior endplate angles with corresponding midpoint coordinates for each vertebra, preserving the anatomical reality of vertebral wedging in progressive AIS. Our approach combines an HRNet backbone with Swin-Transformer modules and biomechanically informed constraints for enhanced feature extraction. We employ Singular Value Decomposition (SVD) to analyze angle predictions directly from vertebral morphology, enabling flexible detection of diverse scoliosis patterns without predefined curve assumptions. Using 630 full-spine anteroposterior radiographs from patients aged 10-18 years with rigorous dual-rater annotation, our method achieved 83.45% diagnostic accuracy and 2.55° mean absolute error. The framework demonstrates exceptional generalization capability on out-of-distribution cases. Additionally, we introduce the Vertebral Wedging Index (VWI), a novel metric quantifying vertebral deformation. Longitudinal analysis revealed VWI's significant prognostic correlation with curve progression while traditional Cobb angles showed no correlation, providing robust support for early AIS detection, personalized treatment planning, and progression monitoring.

脊柱侧弯深度学习医学影像量化指标

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