用视觉引导的扩散模型提升脑肿瘤检测与分割精度
VGDM: Vision-Guided Diffusion Model for Brain Tumor Detection and Segmentation
- 以视觉变换器为核心,结合扩散过程进行迭代去噪
- 在Dice和Hausdorff距离上均优于传统U-Net基线
- 适合需要高精度边界分割的神经肿瘤临床应用
从磁共振成像(MRI)中准确检测和分割脑肿瘤对诊断、治疗规划和临床监测至关重要。尽管卷积网络如U-Net长期作为医学图像分割的骨干,但其难以捕捉长程依赖关系,限制了对复杂肿瘤结构的性能表现。最近的扩散模型在生成高保真医学图像和细化分割边界方面展现出强大潜力。本文提出VGDM:一种基于视觉引导的扩散模型框架,用于脑肿瘤检测与分割。通过将视觉变换器嵌入扩散过程核心,模型利用全局上下文推理与迭代去噪,提升了体积准确性与边界精度。变换器主干增强了对整个MRI体积空间关系的建模能力,而扩散精修则减少了体素级误差并恢复了细粒度肿瘤细节。该混合设计为神经肿瘤学中的鲁棒性与可扩展性提供了新路径,超越了传统U-Net基线。在多个脑肿瘤MRI数据集上的实验验证表明,该方法在Dice相似性与豪斯多夫距离指标上均实现稳定提升,证明了基于变换器引导的扩散模型在推进肿瘤分割最先进水平方面的潜力。
原文摘要 · Abstract (English)
Accurate detection and segmentation of brain tumors from magnetic resonance imaging (MRI) are essential for diagnosis, treatment planning, and clinical monitoring. While convolutional architectures such as U-Net have long been the backbone of medical image segmentation, their limited capacity to capture long-range dependencies constrains performance on complex tumor structures. Recent advances in diffusion models have demonstrated strong potential for generating high-fidelity medical images and refining segmentation boundaries. In this work, we propose VGDM: Vision-Guided Diffusion Model for Brain Tumor Detection and Segmentation framework, a transformer-driven diffusion framework for brain tumor detection and segmentation. By embedding a vision transformer at the core of the diffusion process, the model leverages global contextual reasoning together with iterative denoising to enhance both volumetric accuracy and boundary precision. The transformer backbone enables more effective modeling of spatial relationships across entire MRI volumes, while diffusion refinement mitigates voxel-level errors and recovers fine-grained tumor details. This hybrid design provides a pathway toward improved robustness and scalability in neuro-oncology, moving beyond conventional U-Net baselines. Experimental validation on MRI brain tumor datasets demonstrates consistent gains in Dice similarity and Hausdorff distance, underscoring the potential of transformer-guided diffusion models to advance the state of the art in tumor segmentation.
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