arXiv:2510.02109eess.IVcs.AI2025-10中稿 · publication in the…

构建乳腺MRI数据集,揭示模型如何误用非临床特征。

SpurBreast: A Curated Dataset for Investigating Spurious Correlations in Real-world Breast MRI Classification

  • 设计含人为干扰信号的乳腺MRI数据集,模拟真实世界偏差
  • 发现磁场强度与图像方向是两大主要虚假关联信号
  • 提供对比数据集,助力研究模型泛化与鲁棒性

深度神经网络在医学影像中表现卓越,但其实际应用受制于虚假相关性——模型可能学习非临床特征而非真正医学模式。现有医疗影像数据集未系统设计用于研究此问题,主要受限于版权约束和患者附加数据不足。为此,我们推出SpurBreast,一个经过精心设计的乳腺MRI数据集,有意引入虚假相关性以评估其对模型性能的影响。通过对超过100个涉及患者、设备和成像协议的特征分析,识别出两大主导虚假信号:磁场均强(影响整幅图像的全局特征)和图像方向(影响空间对齐的局部特征)。通过受控数据集划分,我们证明深度神经网络可利用这些非临床信号,在验证集上获得高准确率,但在无偏测试集上严重失效。除含虚假相关性的数据集外,我们还提供无虚假相关性的基准数据集,使研究者能系统评估临床相关与无关特征、不确定性估计、对抗鲁棒性及泛化策略。模型与数据集已公开于 https://github.com/utkuozbulak/spurbreast。

原文摘要 · Abstract (English)

Deep neural networks (DNNs) have demonstrated remarkable success in medical imaging, yet their real-world deployment remains challenging due to spurious correlations, where models can learn non-clinical features instead of meaningful medical patterns. Existing medical imaging datasets are not designed to systematically study this issue, largely due to restrictive licensing and limited supplementary patient data. To address this gap, we introduce SpurBreast, a curated breast MRI dataset that intentionally incorporates spurious correlations to evaluate their impact on model performance. Analyzing over 100 features involving patient, device, and imaging protocol, we identify two dominant spurious signals: magnetic field strength (a global feature influencing the entire image) and image orientation (a local feature affecting spatial alignment). Through controlled dataset splits, we demonstrate that DNNs can exploit these non-clinical signals, achieving high validation accuracy while failing to generalize to unbiased test data. Alongside these two datasets containing spurious correlations, we also provide benchmark datasets without spurious correlations, allowing researchers to systematically investigate clinically relevant and irrelevant features, uncertainty estimation, adversarial robustness, and generalization strategies. Models and datasets are available at https://github.com/utkuozbulak/spurbreast.

医学影像虚假相关数据集乳腺MRI

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