arXiv:2510.04312cs.CV2025-10NeurIPS被引 10

首个多中心帕金森步态数据集,助力精准临床评估

CARE-PD: A Multi-Site Anonymized Clinical Dataset for Parkinson's Disease Gait Assessment

  • 将9个中心的步态视频统一转为匿名3D人体网格数据
  • 预训练可使步态误差降为7.5毫米,疾病严重度识别准确率提升17个百分点
  • 适合医学影像、运动分析与人工智能交叉研究者使用

帕金森病(PD)的客观步态评估受限于缺乏大规模、多样且临床标注的运动数据集。我们推出CARE-PD,目前公开可用的最大3D网格步态数据集,涵盖来自8家临床中心的9个队列。所有记录(RGB视频或动作捕捉)均通过统一预处理流程转换为匿名SMPL人体网格。CARE-PD支持两大基准任务:监督式临床评分预测(估算统一帕金森病评定量表,UPDRS步态评分)与无监督运动预训练任务(2D到3D关键点恢复及全身3D重建)。临床预测在四种泛化协议下评估:数据集内、跨数据集、留一数据集外以及多数据集域内适应。为验证临床相关性,我们对比了先进运动编码器与传统步态特征基线,发现编码器始终优于手工特征。在CARE-PD上预训练后,平均关节位置误差(MPJPE)从60.8毫米降至7.5毫米,帕金森病严重程度宏平均F1值提升17个百分点,凸显临床标注、多样化数据的价值。CARE-PD及所有基准代码已开放用于非商业研究,网址:https://neurips2025.care-pd.ca/

原文摘要 · Abstract (English)

Objective gait assessment in Parkinson's Disease (PD) is limited by the absence of large, diverse, and clinically annotated motion datasets. We introduce CARE-PD, the largest publicly available archive of 3D mesh gait data for PD, and the first multi-site collection spanning 9 cohorts from 8 clinical centers. All recordings (RGB video or motion capture) are converted into anonymized SMPL meshes via a harmonized preprocessing pipeline. CARE-PD supports two key benchmarks: supervised clinical score prediction (estimating Unified Parkinson's Disease Rating Scale, UPDRS, gait scores) and unsupervised motion pretext tasks (2D-to-3D keypoint lifting and full-body 3D reconstruction). Clinical prediction is evaluated under four generalization protocols: within-dataset, cross-dataset, leave-one-dataset-out, and multi-dataset in-domain adaptation. To assess clinical relevance, we compare state-of-the-art motion encoders with a traditional gait-feature baseline, finding that encoders consistently outperform handcrafted features. Pretraining on CARE-PD reduces MPJPE (from 60.8mm to 7.5mm) and boosts PD severity macro-F1 by 17 percentage points, underscoring the value of clinically curated, diverse training data. CARE-PD and all benchmark code are released for non-commercial research at https://neurips2025.care-pd.ca/.

帕金森病步态分析3D人体建模医学数据集

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