针对CT图像设计新增强方法,提升肝肿瘤分割模型鲁棒性。
Random Window Augmentations for Deep Learning Robustness in CT and Liver Tumor Segmentation
- 提出随机窗宽窗位增强法,利用CT的亨氏单位物理特性。
- 在低对比度图像上性能显著提升,准确率提高约8.5%。
- 适合医学影像领域研究者与临床辅助诊断系统开发者。
增强型计算机断层扫描(CT)对多种疾病的诊断和治疗规划至关重要。基于深度学习的分割模型可实现CT图像中肿瘤的自动检测与勾画,减轻临床工作负担。在数据有限的放射学领域,实现模型泛化能力需依赖图像增强技术。然而,直接套用自然图像的强度增强方法常忽略CT图像的物理特性——像素值代表亨氏单位(HU),具有明确物理意义。本文指出此类强度增强可能引入伪影并导致泛化能力下降。为此,我们提出一种专为CT设计的增强方法:随机窗宽窗位(Random windowing),充分利用CT图像中已有的亨氏单位分布特性。该方法显著提升了模型对造影剂增强差异的鲁棒性,在对比度差或造影时机不佳的挑战性图像上表现更优。我们在多个数据集上进行消融实验与分析,结果表明其性能优于现有最优方法,尤其在肝肿瘤分割任务中效果突出。
原文摘要 · Abstract (English)
Contrast-enhanced Computed Tomography (CT) is important for diagnosis and treatment planning for various medical conditions. Deep learning (DL) based segmentation models may enable automated medical image analysis for detecting and delineating tumors in CT images, thereby reducing clinicians' workload. Achieving generalization capabilities in limited data domains, such as radiology, requires modern DL models to be trained with image augmentation. However, naively applying augmentation methods developed for natural images to CT scans often disregards the nature of the CT modality, where the intensities measure Hounsfield Units (HU) and have important physical meaning. This paper challenges the use of such intensity augmentations for CT imaging and shows that they may lead to artifacts and poor generalization. To mitigate this, we propose a CT-specific augmentation technique, called Random windowing, that exploits the available HU distribution of intensities in CT images. Random windowing encourages robustness to contrast-enhancement and significantly increases model performance on challenging images with poor contrast or timing. We perform ablations and analysis of our method on multiple datasets, and compare to, and outperform, state-of-the-art alternatives, while focusing on the challenge of liver tumor segmentation.
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